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How to get fromAppleton to Louisvilleby plane, bus, train, bus (Greyhound, Flixbus, Amtrak), car, taxi, or bus (Flixbus, Amtrak)

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There are 7 ways to get from Appleton to Louisville by plane, bus, train, bus (Greyhound, Flixbus, Amtrak), car, taxi, or bus (Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Appleton International Airport to Louisville International Airport

    best
    1. Fly from Appleton International Airport (ATW) to Louisville International Airport (SDF)plane plane ATW - SDF
    5h 56m
    $115–620

  2. Drive  483.2 mi

    cheapest
    1. Drive from Appleton to Louisvillecar car 483.2 mi
    8h 28m
    $80–116

  3. Bus, train

    1. Take the bus from Oshkosh to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    13h 28m
    $235–370

  4. Bus

    1. Take the bus from Oshkosh to Milwaukeebus bus
    2. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Union Station to Louisville, KYbus bus
    13h 55m
    $115–148

  5. Fly Appleton International Airport to Blue Grass Airport, drive

    1. Fly from Appleton International Airport (ATW) to Blue Grass Airport (LEX)plane plane ATW - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 42m
    $85–395

  6. Taxi to Green Bay, fly to Louisville International Airport

    1. Take the taxi from Appleton to Green Bay (GRB)taxi taxi
    2. Fly from Green Bay (GRB) to Louisville International Airport (SDF)plane plane GRB - SDF
    5h 53m
    $200–720

  7. Bus via Lafayette

    1. Take the bus from Oshkosh to Milwaukeebus bus
    2. Take the bus from Milwaukee Mitchell Airport to Lafayette Bus Stopbus bus
    3. Take the bus from Lafayette Amtrak Station to Louisville, KYbus bus
    14h 51m
    $112–165

Appleton International Airport (ATW) to Louisville International Airport (SDF) flights

Calendar87Weekly Planes
Duration5h 44mAverage Duration
Ticket$100Cheapest Price
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Comparing Your Travel Options

Map of how to get from Appleton to Louisville.ExpandLaunch map view
  • Distance: 454.5 mi
  • Duration: 5h 56m

What companies run services between Appleton, WI, USA and Louisville, KY, USA?

United Airlines, Delta, and two other airlines fly from Appleton International Airport (ATW) to Louisville International Airport (SDF) every 2 hours. Alternatively, you can take a bus from Prospect and Walnut to Louisville, KY via Church @ Doty - Neenah Transit Center, Oshkosh, Milwaukee, Milwaukee Intermodal Station, Chicago Bus Station, and Chicago Union Station in around 13h 55m.

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