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How to get fromAvignon to Mainzby train (TGV), bus, train, car, or plane

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There are 9 ways to get from Avignon to Mainz by train (TGV), bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Avignon Tgv to Mannheim Hbftrain train Tgv
    2. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    8h 7m
    €181–261

  2. Bus, train

    cheapest
    1. Take the bus from Avignon - Le Pontet - Le Lac Stop to Mannheim - Bus Stationbus bus BlaBlaCar Bus
    2. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    13h 45m
    €77–132

  3. Drive  878.3 km

    1. Drive from Avignon to Mainzcar car 878.3 km
    8h 16m
    €161–233

  4. Train to Marseille Provence Airport, fly to Frankfurt

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Frankfurt (FRA)plane plane MRS - FRA
    5h 6m
    €106–300

  5. Bus

    1. Take the bus from AVIGNON, Parking Autocars Saint-Benezet, Boulevard du Rhône to FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str.bus bus
    14h 6m
    €137

  6. Train to Lyon–Saint Exupéry Airport, fly to Frankfurt

    1. Take the train from Avignon Tgv to Lyon-Saint Exupery Tgvtrain train
    2. Fly from Lyon–Saint Exupéry Airport (LYS) to Frankfurt (FRA)plane plane LYS - FRA
    4h 50m
    €140–397

  7. Train to Geneva International Airport, fly to Frankfurt

    1. Take the train from Avignon Tgv to Genevetrain train
    2. Fly from Geneva International Airport (GVA) to Frankfurt (FRA)plane plane GVA - FRA
    7h 10m
    €192–392

  8. Train to Marseille Provence Airport, fly to Strasbourg International Airport, train

    1. Take the train from Avignon Tgv to Aix En Provence Tgvtrain train
    2. Fly from Marseille Provence Airport (MRS) to Strasbourg International Airport (SXB)plane plane MRS - SXB
    3. Take the train from Strasbourg to Mannheim Hbftrain train
    4. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train
    7h 19m
    €86–376

  9. Train, train to Nice Côte D'Azur International Airport, fly to Frankfurt

    1. Take the train from Avignon Tgv to Marseille St Charlestrain train
    2. Take the train from Marseille-Saint-Charles to Nice-Saint-Augustintrain train
    3. Fly from Nice Côte D'Azur International Airport (NCE) to Frankfurt (FRA)plane plane NCE - FRA
    8h 20m
    €192–378

Avignon to Mainz by train

Calendar14Weekly Trains
Duration8h 7mAverage Duration
Ticket€181Cheapest Price
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Comparing Your Travel Options

Map of how to get from Avignon to Mainz.ExpandLaunch map view
  • Distance: 935.3 km
  • Duration: 8h 7m

What companies run services between Avignon, France and Mainz, Germany?

You can take a train from Avignon Tgv to Mainz, Römisches Theater via Mannheim Hbf and Mannheim, Hauptbahnhof in around 8h 7m. Alternatively, Sindbad operates a bus from AVIGNON, Parking Autocars Saint-Benezet, Boulevard du Rhône to FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str. once a week. Tickets cost €126 and the journey takes 13h 30m.

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