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How to get fromBoston to Des Moinesby ferry, plane, train, bus, bus (Flixbus, Greyhound), car, or bus (Greyhound, Flixbus)

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There are 7 ways to get from Boston to Des Moines by ferry, plane, train, bus, bus (Flixbus, Greyhound), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Ferry to Boston Logan Airport, fly

    best
    1. Take the ferry from Long Wharf to Logan Airport Ferry Terminalferry ferry
    2. Fly from Boston Logan Airport (BOS) to Des Moines (DSM)plane plane BOS - DSM
    5h 2m
    $132–583
  2. Train, bus

    1. Take the train from Boston to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    30h 1m
    $619–947
  3. Bus

    1. Take the bus from Boston to New York Midtownbus bus
    2. Take the bus from New York Midtown to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    33h 15m
    $244–380
  4. Drive  1,295.8 mi

    1. Drive from Boston to Des Moinescar car 1,295.8 mi
    22h 1m
    $214–309
  5. Train to Theodore Francis Green State Airport, fly

    1. Take the train from South Station to TF Green Airporttrain train
    2. Fly from Theodore Francis Green State Airport (PVD) to Des Moines (DSM)plane plane PVD - DSM
    8h 4m
    $138–589
  6. Train, bus via Galesburg

    1. Take the train from Boston to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    3. Take the bus from Galesburg to Des Moinesbus bus
    31h 53m
    $679–1,052
  7. Bus via Indianapolis

    1. Take the bus from Boston to Newark Penn Stationbus bus
    2. Take the bus from Newark Penn Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Des Moinesbus bus
    33h 35m
    $251–399

Boston to Des Moines by train, foot, and bus

Calendar7Weekly Services
Duration30h 1mAverage Duration
Ticket$619Cheapest Price
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Comparing Your Travel Options

What companies run services between Boston, MA, USA and Des Moines, IA, USA?

You can take a bus from Boston to Des Moines via New York Midtown and Chicago Bus Station in around 33h 15m.

Airlines
Train operators
Bus operators
Ferry operators

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Need to know: Greyhound

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