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How to get fromCape Cod to Myrtle Beachby plane, bus, train, bus (Greyhound, Flixbus), car, or bus (Greyhound)

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There are 9 ways to get from Cape Cod to Myrtle Beach by plane, bus, train, bus (Greyhound, Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Barnstable Municipal Airport to Myrtle Beach

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Myrtle Beach (MYR)plane plane HYA - MYR
    6h 55m
    $97–475

  2. Bus to Boston Logan Airport, fly to Myrtle Beach

    cheapest
    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Myrtle Beach (MYR)plane plane BOS - MYR
    6h 31m
    $95–420

  3. Bus, train

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from Boston to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Fayetteville Amtrak Stationtrain train
    4. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    23h 29m
    $461–730

  4. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to Fayetteville Bus Stationbus bus
    4. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    24h 34m
    $179–280

  5. Drive  890.1 mi

    1. Drive from Cape Cod to Myrtle Beachcar car 890.1 mi
    16h 57m
    $147–213

  6. Bus, train to Theodore Francis Green State Airport, fly to Myrtle Beach

    1. Take the bus from Hyannis to Bostonbus bus
    2. Take the train from South Station to TF Green Airporttrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Myrtle Beach (MYR)plane plane PVD - MYR
    8h 43m
    $99–425

  7. Bus to Boston Logan Airport, fly to Wilmington International Airport, bus

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Wilmington International Airport (ILM)plane plane BOS - ILM
    3. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    9h 1m
    $141–615

  8. Bus, train via New York

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Fayetteville Amtrak Stationtrain train
    4. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    23h 40m
    $404–1,300

  9. Bus via Chesapeake

    1. Take the bus from Hyannis to Providencebus bus
    2. Take the bus from Providence to New Yorkbus bus
    3. Take the bus from Times Square – 37th St. to Norfolk, VA - Best Squarebus bus
    4. Take the bus from Norfolk to Myrtle Beach Bus Stationbus bus
    26h 10m
    $161–248

Cape Cod to Myrtle Beach by bus, foot, and train

Calendar7Weekly Services
Duration23h 29mAverage Duration
Ticket$461Cheapest Price
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Comparing Your Travel Options

Map of how to get from Cape Cod to Myrtle Beach.ExpandLaunch map view
  • Distance: 735.1 mi
  • Duration: 6h 55m

What companies run services between Cape Cod, MA, USA and Myrtle Beach, SC, USA?

American Airlines, Cape Air, and two other airlines fly from Barnstable Municipal Airport (HYA) to Myrtle Beach (MYR) twice daily. Alternatively, you can take a bus from Town Hall Lawton Bus Shelter to Myrtle Beach Bus Station via Hyannis Transportation Center, Boston, South Station, Boston, Newark Penn Station, and Fayetteville Bus Station in around 24h 34m.

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