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How to get fromCologne to Sienaby train, plane, train (Trenitalia), bus, night train, car, or car train

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There are 12 ways to get from Cologne to Siena by train, plane, train (Trenitalia), bus, night train, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Düsseldorf International Airport, fly to Florence Peretola Airport, train

    best
    1. Take the train from Koeln Hbf to Duesseldorf Flughafentrain train
    2. Fly from Düsseldorf International Airport (DUS) to Florence Peretola Airport (FLR)plane plane DUS - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    6h 56m
    €124–297
  2. Fly Cologne Bonn Airport to Bologna Guglielmo Marconi Airport, train

    cheapest
    1. Fly from Cologne Bonn Airport (CGN) to Bologna Guglielmo Marconi Airport (BLQ)plane plane CGN - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    6h 39m
    €78–253
  3. Train

    1. Take the train from Koeln Hbf to Frankfurt(Main)Hbftrain train Ice
    2. Take the train from Frankfurt to Chiassotrain train Ec
    3. Take the train from Chiasso to Milano Centraletrain train S11
    4. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Sienatrain train Re
    14h 32m
    €277–485
  4. Bus

    1. Take the bus from Cologne to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    18h 20m
    €153–210
  5. Train, night train

    1. Take the train from Köln Messe/Deutz Bf to Hauptbahnhoftrain train 47 / ...
    2. Take the nighttrain from Stuttgart Hbf to Venezia Mestrenighttrain night train Nj
    3. Take the train from Venezia Mestre to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    19h 19m
    €123–308
  6. Fly Cologne Bonn Airport to Florence Peretola Airport, train

    1. Fly from Cologne Bonn Airport (CGN) to Florence Peretola Airport (FLR)plane plane CGN - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    7h 42m
    €125–324
  7. Train to Frankfurt, fly to Florence Peretola Airport, train

    1. Take the train from Köln Messe/Deutz Bf to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    6h 47m
    €152–387
  8. Train to Düsseldorf International Airport, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Koeln Hbf to Duesseldorf Flughafentrain train
    2. Fly from Düsseldorf International Airport (DUS) to Bologna Guglielmo Marconi Airport (BLQ)plane plane DUS - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    7h 28m
    €117–286
  9. Train to Frankfurt, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Köln Messe/Deutz Bf to Frankfurttrain train
    2. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    7h 14m
    €135–346
  10. Drive, car train

    1. Drive from Cologne to Fuldacar car
    2. Take the cartrain from Fulda to Villach Hbfcartrain train
    3. Drive from Villach Hbf to Sienacar car
    17h 5m
    €233–323
  11. Bus via Flughafen Köln/Bonn Bf

    1. Take the bus from Cologne Airport CGN to Florence Villa Constanza Bus Stationbus bus N537
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus N528 / ...
    19h 54m
    €107–175
  12. Drive  1,185.9 km

    1. Drive from Cologne to Sienacar car 1,185.9 km
    11h 11m
    €214–308

Cologne to Siena by train

Calendar6Weekly Trains
Duration14h 32mAverage Duration
Ticket€277Cheapest Price
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Comparing Your Travel Options

What companies run services between Cologne, Germany and Siena, Italy?

You can take a train from Koeln Hbf to Siena via Frankfurt(Main)Hbf, Frankfurt, Chiasso, Milano Centrale, and Firenze S.M.N. in around 14h 32m. Alternatively, you can take a bus from Cologne to Siena via Florence Villa Constanza Bus Station in around 18h 20m.

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