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How to get fromFlorida to Missouriby plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train

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There are 12 ways to get from Florida to Missouri by plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Jacksonville to Lambert–St. Louis International Airport

    best
    1. Fly from Jacksonville (JAX) to Lambert–St. Louis International Airport (STL)plane plane JAX - STL
    4h 54m
    $115–656

  2. Bus

    1. Take the bus from Jacksonville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    25h 33m
    $202–328

  3. Train (Amtrak)

    1. Take the train from Jacksonville to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to Kansas Citytrain train Southwest Chief / ...
    43h 57m
    $1,094–1,786

  4. Drive  1,088.8 mi

    1. Drive from Jacksonville to Kansas Citycar car 1,088.8 mi
    20h 1m
    $180–260

  5. Fly Tampa to Lambert–St. Louis International Airport

    1. Fly from Tampa (TPA) to Lambert–St. Louis International Airport (STL)plane plane TPA - STL
    4h 49m
    $115–605

  6. Fly Orlando to Lambert–St. Louis International Airport

    1. Fly from Orlando (MCO) to Lambert–St. Louis International Airport (STL)plane plane MCO - STL
    4h 57m
    $175–555

  7. Fly Miami International Airport to Lambert–St. Louis International Airport

    1. Fly from Miami International Airport (MIA) to Lambert–St. Louis International Airport (STL)plane plane MIA - STL
    4h 54m
    $116–556

  8. Fly Fort Lauderdale–Hollywood International Airport to Lambert–St. Louis International Airport

    1. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Lambert–St. Louis International Airport (STL)plane plane FLL - STL
    5h 2m
    $165–806

  9. Fly Orlando to Kansas City

    1. Fly from Orlando (MCO) to Kansas City (MCI)plane plane MCO - MCI
    6h 19m
    $222–702

  10. Fly Tampa to Kansas City

    1. Fly from Tampa (TPA) to Kansas City (MCI)plane plane TPA - MCI
    6h 16m
    $152–802

  11. Fly Ft. Myers to Lambert–St. Louis International Airport

    1. Fly from Ft. Myers (RSW) to Lambert–St. Louis International Airport (STL)plane plane RSW - STL
    6h 10m
    $136–708

  12. Bus, train

    1. Take the bus from Jacksonville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Kansas Citytrain train
    26h 12m
    $310–491

Florida to Missouri by bus

Calendar12Weekly Buses
Duration25h 33mAverage Duration
Ticket$202Cheapest Price
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Comparing Your Travel Options

Map of how to get from Florida to Missouri.ExpandLaunch map view
  • Distance: 783.5 mi
  • Duration: 4h 54m

What companies run services between Florida, USA and Missouri, USA?

Southwest Airlines, Delta, and American Airlines fly from Jacksonville (JAX) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a bus from Newnan St + Ashley St to Kansas City Bus Station via JRTC Bay J, Jacksonville, Atlanta Bus Station, and St Louis Bus Station in around 25h 33m.

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Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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