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How to get fromFrederick to Indianaby bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or subway

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There are 9 ways to get from Frederick to Indiana by bus, plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Baltimore-Washington International Airport, fly to Indianapolis

    best
    1. Take the bus from Frederick to Baltimorebus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Indianapolis (IND)plane plane BWI - IND
    5h 21m
    $189–756

  2. Train, subway to Washington Dulles International Airport, fly to South Bend

    cheapest
    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to South Bend (SBN)plane plane IAD - SBN
    4. Take the train from South Bend Airport to Gary Metro Centertrain train
    7h 32m
    $82–409

  3. Bus

    1. Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus bus Greyhound US0164 / ...
    2. Take the bus from Pittsburgh Intermodal Station to Indianapolisbus bus FlixBus N2642 / ...
    12h 25m
    $89–135

  4. Train

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train Marc
    2. Take the train from Washington Union Station to Indianapolistrain train Cardinal
    20h 56m
    $392–662

  5. Drive  518.1 mi

    1. Drive from Frederick to Indianapoliscar car 518.1 mi
    9h 14m
    $86–124

  6. Train to Ronald Reagan Washington National Airport, fly to Indianapolis

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Indianapolis (IND)plane plane DCA - IND
    5h 56m
    $138–819

  7. Train, subway to Washington Dulles International Airport, fly to Indianapolis

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Take the subway from Metro Center, Blue/Orange/Silver Line Center Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    3. Fly from Washington Dulles International Airport (IAD) to Indianapolis (IND)plane plane IAD - IND
    6h 23m
    $98–568

  8. Bus to Baltimore-Washington International Airport, fly to Chicago Midway International Airport, train

    1. Take the bus from Frederick to Baltimorebus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Chicago Midway International Airport (MDW)plane plane BWI - MDW
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    6h 20m
    $257–359

  9. Train to Ronald Reagan Washington National Airport, fly to Chicago Midway International Airport, train

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Chicago Midway International Airport (MDW)plane plane DCA - MDW
    3. Take the train from Van Buren St. to Gary Metro Centertrain train
    6h 46m
    $126–682

Frederick to Indiana by bus

Calendar9Weekly Buses
Duration12h 25mAverage Duration
Ticket$89Cheapest Price
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Comparing Your Travel Options

Map of how to get from Frederick to Indiana.ExpandLaunch map view
  • Distance: 588 mi
  • Duration: 5h 21m

What companies run services between Frederick, MD, USA and Indiana, USA?

You can take a bus from Frederick Bus Station to Indianapolis via Pittsburgh Intermodal Station in around 12h 25m. Alternatively, you can take a train from FREDERICK MARC eb to Indianapolis via Washington Union Station in around 20h 56m.

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