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How to get fromGainesville to Iowaby plane, bus (Flixbus, Greyhound), bus, train, or car

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There are 9 ways to get from Gainesville to Iowa by plane, bus (Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Gainesville Regional Airport to Des Moines

    best
    1. Fly from Gainesville Regional Airport (GNV) to Des Moines (DSM)plane plane GNV - DSM
    6h 18m
    $110–484
  2. Fly Gainesville Regional Airport to Quad City International Airport

    cheapest
    1. Fly from Gainesville Regional Airport (GNV) to Quad City International Airport (MLI)plane plane GNV - MLI
    7h 49m
    $88–444
  3. Bus

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    4. Take the bus from Kansas City to Des Moinesbus bus
    28h 10m
    $233–373
  4. Bus, train

    1. Take the bus from Gainesville to Jacksonvillebus bus
    2. Take the train from Jacksonville to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    45h 35m
    $941–1,532
  5. Drive  1,211.8 mi

    1. Drive from Gainesville to Des Moinescar car 1,211.8 mi
    21h 13m
    $201–289
  6. Fly Gainesville Regional Airport to The Eastern Iowa Airport

    1. Fly from Gainesville Regional Airport (GNV) to The Eastern Iowa Airport (CID)plane plane GNV - CID
    6h 34m
    $132–502
  7. Fly Gainesville Regional Airport to Omaha

    1. Fly from Gainesville Regional Airport (GNV) to Omaha (OMA)plane plane GNV - OMA
    8h 26m
    $134–656
  8. Drive to Orlando Sanford, fly to Des Moines

    1. Drive from Gainesville to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Des Moines (DSM)plane plane SFB - DSM
    5h 31m
    $131–520
  9. Bus, train via Atlanta

    1. Take the bus from Gainesville to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the train from St. Louis to Kansas Citytrain train
    4. Take the bus from Kansas City to Des Moinesbus bus
    30h 36m
    $343–543

Gainesville to Iowa by bus

Calendar12Weekly Buses
Duration28h 10mAverage Duration
Ticket$233Cheapest Price
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Comparing Your Travel Options

What companies run services between Gainesville, FL, USA and Iowa, USA?

Delta and American Airlines fly from Gainesville Regional Airport (GNV) to Des Moines (DSM) every 4 hours. Alternatively, you can take a bus from Gainesville to Des Moines via Atlanta Bus Station, St Louis Bus Station, Kansas City Bus Station, and Kansas City in around 28h 10m.

Airlines
Train operators
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Want to know more about travelling around United States

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Need to know: Greyhound

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