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How to get fromHopkinton to Buffaloby train, plane, bus (Greyhound), train (Amtrak), car, or bus

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There are 6 ways to get from Hopkinton to Buffalo by train, plane, bus (Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, fly to Buffalo Niagara International Airport

    best
    1. Take the train from Southborough to Back Baytrain train
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    6h 28m
    $80–430
  2. Drive  431 mi

    cheapest
    1. Drive from Hopkinton to Buffalocar car 431 mi
    7h 29m
    $72–103
  3. Bus (Greyhound)

    1. Take the bus from Boston to Buffalobus bus Greyhound US0171
    13h 34m
    $84–138
  4. Train (Amtrak)

    1. Take the train from Framingham Amtrak to Buffalo Depew Stationtrain train Lake Shore Limited
    14h 24m
    $256–406
  5. Train, fly to Rochester, bus

    1. Take the train from Southborough to Back Baytrain train
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 53m
    $100–434
  6. Train, bus

    1. Take the train from Southborough to South Stationtrain train
    2. Take the bus from Boston to Ithacabus bus
    3. Take the bus from Ithaca to Buffalobus bus
    15h 35m
    $94–152

Hopkinton to Buffalo by bus (Greyhound)

Calendar7Weekly Buses
Duration13h 34mAverage Duration
Ticket$84Cheapest Price
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Comparing Your Travel Options

What companies run services between Hopkinton, MA, USA and Buffalo, NY, USA?

Greyhound USA operates a bus from Boston to Buffalo once daily. Tickets cost $80–130 and the journey takes 10h 5m. Alternatively, Amtrak operates a train from Framingham Amtrak to Buffalo Depew Station once daily. Tickets cost $250–400 and the journey takes 11h 4m.

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Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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