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How to get fromHyannis to Ithacaby bus (Flixbus), bus, train, car, or plane

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There are 9 ways to get from Hyannis to Ithaca by bus (Flixbus), bus, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Hyannis to Bostonbus bus Bz 0947 / ...
    2. Take the bus from Boston to Ithacabus bus FlixBus 2691
    10h 14m
    $74–119

  2. Fly Barnstable Municipal Airport to Ithaca Tompkins Regional Airport

    cheapest
    1. Fly from Barnstable Municipal Airport (HYA) to Ithaca Tompkins Regional Airport (ITH)plane plane HYA - ITH
    6h 54m
    $50–340

  3. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Utica Amtrak Stationtrain train
    3. Take the bus from Utica Bus Stop to Ithacabus bus
    13h 54m
    $206–313

  4. Drive  390 mi

    1. Drive from Hyannis to Ithacacar car 390 mi
    7h 19m
    $65–93

  5. Fly Barnstable Municipal Airport to Syracuse Hancock International Airport, bus

    1. Fly from Barnstable Municipal Airport (HYA) to Syracuse Hancock International Airport (SYR)plane plane HYA - SYR
    2. Take the bus from Syracuse Bus Station to Ithacabus bus
    7h 37m
    $64–370

  6. Bus via New Haven

    1. Take the bus from Hyannis to Providencebus bus
    2. Take the bus from Providence to New Havenbus bus
    3. Take the bus from New Haven, CT - Union Station to Ithaca, NY - West Ave across from Bakers Flagpolebus bus
    11h 40m
    $126–268

  7. Bus to Boston Logan Airport, fly to Rochester, bus

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane plane BOS - ROC
    3. Take the bus from Rochester to Ithacabus bus
    7h 25m
    $109–475

  8. Bus to Boston Logan Airport, fly to Syracuse Hancock International Airport, bus

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Syracuse Hancock International Airport (SYR)plane plane BOS - SYR
    3. Take the bus from Syracuse Bus Station to Ithacabus bus
    7h 25m
    $78–428

  9. Bus to Boston Logan Airport, fly to Buffalo Niagara International Airport, bus

    1. Take the bus from Hyannis to Bostonbus bus
    2. Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane plane BOS - BUF
    3. Take the bus from Buffalo Niagara International Airport to Ithacabus bus
    8h 46m
    $100–446

Hyannis to Ithaca by bus

Calendar3Weekly Buses
Duration10h 14mAverage Duration
Ticket$74Cheapest Price
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Comparing Your Travel Options

Map of how to get from Hyannis to Ithaca.ExpandLaunch map view
  • Distance: 450.5 mi
  • Duration: 10h 14m

What companies run services between Hyannis, MA, USA and Ithaca, NY, USA?

You can take a bus from Hyannis to Ithaca via Boston in around 10h 14m. Alternatively, JetBlue Airways, Delta, and three other airlines fly from Barnstable Municipal Airport (HYA) to Ithaca Tompkins Regional Airport (ITH) 3 times a day.

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Train operators
Bus operators

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