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How to get fromIowa to Gainesvilleby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 8 ways to get from Iowa to Gainesville by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Gainesville Regional Airport

    best
    1. Fly from Des Moines (DSM) to Gainesville Regional Airport (GNV)plane plane DSM - GNV
    6h 29m
    $111–485

  2. Fly Quad City International Airport to Gainesville Regional Airport

    cheapest
    1. Fly from Quad City International Airport (MLI) to Gainesville Regional Airport (GNV)plane plane MLI - GNV
    7h 35m
    $89–444

  3. Bus

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    27h 20m
    $233–372

  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Jacksonvilletrain train
    3. Take the bus from Jacksonville to Gainesvillebus bus
    45h 50m
    $941–1,533

  5. Drive  1,198 mi

    1. Drive from Des Moines to Gainesvillecar car 1,198 mi
    21h 39m
    $198–286

  6. Fly Des Moines to Orlando Sanford, drive

    1. Fly from Des Moines (DSM) to Orlando Sanford (SFB)plane plane DSM - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Gainesvillecar car
    5h 19m
    $132–520

  7. Fly Omaha to Gainesville Regional Airport

    1. Fly from Omaha (OMA) to Gainesville Regional Airport (GNV)plane plane OMA - GNV
    8h 48m
    $115–555

  8. Bus, train via Atlanta

    1. Take the bus from Des Moines to Kansas Citybus bus
    2. Take the train from Kansas City to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    29h 40m
    $343–542

Iowa to Gainesville by bus

Calendar12Weekly Buses
Duration27h 20mAverage Duration
Ticket$233Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa to Gainesville.ExpandLaunch map view
  • Distance: 1,050.3 mi
  • Duration: 6h 29m

What companies run services between Iowa, USA and Gainesville, FL, USA?

American Airlines and Delta fly from Des Moines (DSM) to Gainesville Regional Airport (GNV) 5 times a day. Alternatively, you can take a bus from Des Moines to Gainesville via Kansas City, Kansas City Bus Station, St Louis Bus Station, and Atlanta Bus Station in around 27h 20m.

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Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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