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How to get fromIowa to Ohioby plane, bus (Greyhound, Flixbus), car, bus, bus (Greyhound), or train

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There are 9 ways to get from Iowa to Ohio by plane, bus (Greyhound, Flixbus), car, bus, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Des Moines to Cleveland-Hopkins International Airport

    best
    1. Fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE)plane plane DSM - CLE
    4h 37m
    $107–526

  2. Drive  619.5 mi

    cheapest
    1. Drive from Des Moines to Columbuscar car 619.5 mi
    11h 29m
    $103–148

  3. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the bus from Chicago Bus Station to Columbusbus bus FlixBus 2511 / ...
    15h 30m
    $123–185

  4. Fly Des Moines to John Glenn Columbus International Airport

    1. Fly from Des Moines (DSM) to John Glenn Columbus International Airport (CMH)plane plane DSM - CMH
    4h 57m
    $106–526

  5. Fly Des Moines to Detroit, bus

    1. Fly from Des Moines (DSM) to Detroit (DTW)plane plane DSM - DTW
    2. Take the bus from Dearborn to Toledobus bus
    5h 20m

  6. Fly Omaha to Cleveland-Hopkins International Airport

    1. Fly from Omaha (OMA) to Cleveland-Hopkins International Airport (CLE)plane plane OMA - CLE
    6h 43m
    $116–656

  7. Fly Omaha to John Glenn Columbus International Airport

    1. Fly from Omaha (OMA) to John Glenn Columbus International Airport (CMH)plane plane OMA - CMH
    7h 16m
    $115–656

  8. Bus via Indianapolis (Greyhound)

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the bus from Indianapolis Union Station to Columbusbus bus Greyhound US0421
    15h 35m
    $118–190

  9. Bus, train

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Toledotrain train
    4. Take the bus from Toledo to Columbusbus bus
    17h 19m
    $273–445

Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE) flights

Calendar122Weekly Planes
Duration5h 25mAverage Duration
Ticket$88Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa to Ohio.ExpandLaunch map view
  • Distance: 629.3 mi
  • Duration: 4h 37m

What companies run services between Iowa, USA and Ohio, USA?

Delta, Southwest Airlines, and two other airlines fly from Des Moines (DSM) to Cleveland-Hopkins International Airport (CLE) hourly. Alternatively, you can take a vehicle from Des Moines to Columbus via Des Moines and Chicago Bus Station in around 15h 30m.

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Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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