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How to get fromIrvine to Durhamby plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

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There are 9 ways to get from Irvine to Durham by plane, bus (Greyhound, Flixbus), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Wayne Airport Orange County to Raleigh-Durham International Airport

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Raleigh-Durham International Airport (RDU)plane plane SNA - RDU
    8h 2m
    $208–908

  2. Train to Los Angeles International Airport, fly to Raleigh-Durham International Airport

    cheapest
    1. Take the train from Tustin to L.A. Union Stationtrain train
    2. Fly from Los Angeles International Airport (LAX) to Raleigh-Durham International Airport (RDU)plane plane LAX - RDU
    9h 8m
    $202–341

  3. Bus

    1. Take the bus from Anaheim Regional Transportation Intermodal Center to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Dallas Bus Stationbus bus
    3. Take the bus from Dallas Bus Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Durhambus bus
    2d 12h
    $468–734

  4. Train (Amtrak)

    1. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the train from Raleigh Union Station to Durham Amtrak Stationtrain train
    2d 22h
    $1,771–2,881

  5. Drive  2,486.9 mi

    1. Drive from Irvine to Durhamcar car 2,486.9 mi
    40h 24m
    $411–594

  6. Train to San Diego International Airport, fly to Raleigh-Durham International Airport

    1. Take the train from Irvine to San Diego Old Town Transportation Centertrain train
    2. Fly from San Diego International Airport (SAN) to Raleigh-Durham International Airport (RDU)plane plane SAN - RDU
    10h 22m
    $212–784

  7. Train to Ontario International Airport, fly to Raleigh-Durham International Airport

    1. Take the train from Tustin to Riverside - Downtowntrain train
    2. Fly from Ontario International Airport (ONT) to Raleigh-Durham International Airport (RDU)plane plane ONT - RDU
    11h 58m
    $227–970

  8. Fly Long Beach Airport to Raleigh-Durham International Airport

    1. Fly from Long Beach Airport (LGB) to Raleigh-Durham International Airport (RDU)plane plane LGB - RDU
    12h 6m
    $336–1,420

  9. Fly John Wayne Airport Orange County to Charlotte Douglas International Airport, train

    1. Fly from John Wayne Airport Orange County (SNA) to Charlotte Douglas International Airport (CLT)plane plane SNA - CLT
    2. Take the train from Charlotte Amtrak Station to Durham Amtrak Stationtrain train
    10h 55m
    $306–788

Irvine to Durham by bus

Calendar14Weekly Buses
Duration2d 12hAverage Duration
Ticket$468Cheapest Price
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Comparing Your Travel Options

Map of how to get from Irvine to Durham.ExpandLaunch map view
  • Distance: 2,227.1 mi
  • Duration: 8h 2m

What companies run services between Irvine, CA, USA and Durham, NC, USA?

Breeze Airways, Delta, and three other airlines fly from John Wayne Airport Orange County (SNA) to Raleigh-Durham International Airport (RDU) every 3 hours. Alternatively, you can take a bus from Main-Harvard to Durham via Artic - Dock 4, Anaheim Regional Transportation Intermodal Center, Los Angeles Union Station, Dallas Bus Station, and Atlanta Bus Station in around 2d 12h.

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Want to know more about travelling around United States

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