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How to get fromIrvine to Iowaby plane, train, bus, bus (Greyhound, Flixbus), or car

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There are 6 ways to get from Irvine to Iowa by plane, train, bus, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly John Wayne Airport Orange County to Des Moines

    best
    1. Fly from John Wayne Airport Orange County (SNA) to Des Moines (DSM)plane plane SNA - DSM
    4h 54m
    $140–395
  2. Train to Los Angeles International Airport, fly to Des Moines

    cheapest
    1. Take the train from Tustin to L.A. Union Stationtrain train
    2. Fly from Los Angeles International Airport (LAX) to Des Moines (DSM)plane plane LAX - DSM
    6h 34m
    $124–328
  3. Train, bus

    1. Take the train from Fullerton Amtrak Station to Kansas Citytrain train Southwest Chief
    2. Take the bus from Kansas City to Des Moinesbus bus Jefferson Lines 804 / ...
    41h 5m
    $1,007–1,584
  4. Bus

    1. Take the bus from Anaheim Regional Transportation Intermodal Center to Los Angeles Union Stationbus bus
    2. Take the bus from Los Angeles Union Station to Tulsa Bus Stationbus bus
    3. Take the bus from Tulsa to Des Moinesbus bus
    46h 20m
    $378–564
  5. Drive  1,681.9 mi

    1. Drive from Irvine to Des Moinescar car 1,681.9 mi
    26h 4m
    $278–402
  6. Fly John Wayne Airport Orange County to Omaha

    1. Fly from John Wayne Airport Orange County (SNA) to Omaha (OMA)plane plane SNA - OMA
    8h 17m
    $165–506

Irvine to Iowa by train, foot, and bus

Calendar7Weekly Services
Duration41h 5mAverage Duration
Ticket$1,007Cheapest Price
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Comparing Your Travel Options

What companies run services between Irvine, CA, USA and Iowa, USA?

Allegiant Air, Southwest Airlines, and four other airlines fly from John Wayne Airport Orange County (SNA) to Des Moines (DSM) every 3 hours. Alternatively, you can take a bus from Main-Harvard to Des Moines via Artic - Dock 4, Anaheim Regional Transportation Intermodal Center, Los Angeles Union Station, and Tulsa in around 46h 20m.

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Need to know: Greyhound

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