There are 9 ways to get from Isernia to Pisa by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Florence
best- Take the train from Isernia to Roma Terminitrain Re
- Take the train from Roma Termini to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Pisa Centraletrain Re
5h 37m€60–103Train, bus
cheapest- Take the train from Isernia to Cassinotrain Re
- Take the bus from Cassino to Pisabus
8h 2m€36–53Bus
- Take the bus from Isernia to Roma, Autostazione Tiburtinabus Campobasso / ...
- Take the bus from Roma, Autostazione Tiburtina to Pisabus N1508 / ...
7h 45m€38–68Drive 507.2 km
- Drive from Isernia to Pisacar 507.2 km
5h 4m€92–132Train to Fiumicino International Airport, fly to Florence Peretola Airport, train
- Take the train from Isernia to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Florence Peretola Airport (FLR)plane FCO - FLR
- Take the train from Firenze S.M.N. to Pisa Centraletrain
6h 42m€96–251Train (Trenitalia)
- Take the train from Isernia to Roma Terminitrain Re
- Take the train from Roma Termini to Pisa Centraletrain Fb / ...
5h 39m€57–110Bus, train to Bari Karol Wojtyła Airport, fly to Pisa International Airport
- Take the bus from Isernia to Foggiabus
- Take the train from Foggia to Bari Centraletrain
- Fly from Bari Karol Wojtyła Airport (BRI) to Pisa International Airport (PSA)plane BRI - PSA
6h 16m€66–253Train to Fiumicino International Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Isernia to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Bologna Guglielmo Marconi Airport (BLQ)plane FCO - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Pisa Centraletrain
7h 29m€99–250Train to Fiumicino International Airport, fly to Genoa Cristoforo Colombo Airport, train
- Take the train from Isernia to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Genoa Cristoforo Colombo Airport (GOA)plane FCO - GOA
- Take the train from Genova P.Za Principe to Pisa Centraletrain
8h 6m€88–241
Isernia to Pisa by train
Comparing Your Travel Options
The cheapest way to get from Isernia to Pisa is to train and bus which costs €35 - €55 and takes 8h 2m.
The fastest way to get from Isernia to Pisa is to drive which takes 5h 4m and costs €90 - €140.
No, there is no direct bus from Isernia to Pisa. However, there are services departing from Isernia and arriving at Pisa via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 7h 45m.
No, there is no direct train from Isernia to Pisa. However, there are services departing from Isernia and arriving at Pisa Centrale via Roma Termini and Firenze S.M.N.. The journey, including transfers, takes approximately 5h 37m.
The distance between Isernia and Pisa is 525 km. The road distance is 507.2 km.
The best way to get from Isernia to Pisa without a car is to train via Florence which takes 5h 37m and costs €60 - €110.
It takes approximately 5h 37m to get from Isernia to Pisa, including transfers.
Isernia to Pisa bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., depart from Isernia station.
Isernia to Pisa train services, operated by Trenitalia, depart from Isernia station.
The best way to get from Isernia to Pisa is to train via Florence which takes 5h 37m and costs €60 - €110. Alternatively, you can bus, which costs €35 - €70 and takes 7h 45m.
What companies run services between Isernia, Italy and Pisa, Italy?
You can take a train from Isernia to Pisa Centrale via Roma Termini and Firenze S.M.N. in around 5h 37m. Alternatively, you can take a bus from Isernia to Pisa via Roma, Autostazione Tiburtina in around 7h 45m.
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Florence Peretola Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- €60–150
Flights from Fiumicino International Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €55–140
Flights from Fiumicino International Airport to Genoa Cristoforo Colombo Airport
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- €50–170
- Website
- ryanair.com
Flights from Bari Karol Wojtyła Airport to Pisa International Airport
- Ave. Duration
- 1h 20m
- When
- Friday, Monday, Saturday, Sunday, and Thursday
- Estimated price
- €35–190
- Website
- aeroitalia.com
Flights from Fiumicino International Airport to Genoa Cristoforo Colombo Airport
- Ave. Duration
- 1h
- When
- Every day
- Estimated price
- €35–140
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 19m
- Frequency
- Every 4 hours
- Estimated price
- €22–30
- Website
- Trenitalia
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 4h 25m
- Frequency
- Every 4 hours
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 19m
- Frequency
- Every 4 hours
- Estimated price
- €22–30
- Website
- Trenitalia
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 19m
- Frequency
- Every 4 hours
- Estimated price
- €22–30
- Website
- Trenitalia
Train from Roma Termini to Pisa Centrale
- Ave. Duration
- 4h 13m
- Frequency
- Every 2 hours
- Estimated price
- €35–55
- Website
- Trenitalia
Train from Isernia to Cassino
- Ave. Duration
- 41 min
- Frequency
- Every 4 hours
- Estimated price
- €6–9
- Website
- Trenitalia
Train from Foggia to Bari Centrale
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €14–20
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 19m
- Frequency
- Every 4 hours
- Estimated price
- €22–30
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 19m
- Frequency
- Every 4 hours
- Estimated price
- €22–30
- Website
- Trenitalia
Train from Genova P.Za Principe to Pisa Centrale
- Ave. Duration
- 3h 32m
- Frequency
- Twice a week
- Estimated price
- €19–27
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 41m
- Frequency
- Every 20 minutes
- Estimated price
- €35–60
- Website
- Trenitalia Frecce
Train from Roma Termini to Pisa Centrale
- Ave. Duration
- 2h 56m
- Frequency
- Every 2 hours
- Estimated price
- €45–80
- Website
- Trenitalia Frecce
Train from Foggia to Bari Centrale
- Ave. Duration
- 1h 6m
- Frequency
- Hourly
- Estimated price
- €17–29
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 38 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–21
- Website
- Trenitalia Frecce
Train from Genova P.Za Principe to Pisa Centrale
- Ave. Duration
- 1h 57m
- Frequency
- Every 2 hours
- Estimated price
- €22–40
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 36m
- Frequency
- Once daily
- Estimated price
- €30–50
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 38 min
- Frequency
- Twice daily
- Estimated price
- €10–18
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- €29–55
- Website
- Trenitalia Intercity
Train from Roma Termini to Pisa Centrale
- Ave. Duration
- 3h 3m
- Frequency
- 4 times a day
- Estimated price
- €35–65
- Website
- Trenitalia Intercity
Train from Foggia to Bari Centrale
- Ave. Duration
- 1h 14m
- Frequency
- Hourly
- Estimated price
- €13–24
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €10–18
- Website
- Trenitalia Intercity
Train from Genova P.Za Principe to Pisa Centrale
- Ave. Duration
- 2h 37m
- Frequency
- Hourly
- Estimated price
- €18–35
- Website
- Trenitalia Intercity
- Phone
- +39 0874 64744
- [email protected]
- Website
- atm-molise.it
Bus from Isernia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Isernia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- €15–23
- Website
- Flixbus
Bus from Roma, Autostazione Tiburtina to Pisa
- Ave. Duration
- 4h 35m
- Frequency
- 3 times a day
- Estimated price
- €29–45
- Website
- Flixbus
Bus from Isernia to Foggia
- Ave. Duration
- 2h 4m
- Frequency
- Once daily
- Estimated price
- €12–19
- Website
- Flixbus
- Phone
- +39 089 233 899
- [email protected]
- Website
- Curcio Viaggi
Bus from Cassino to Pisa
- Ave. Duration
- 6h 15m
- Frequency
- Once daily
- Estimated price
- €30–45
- Website
- Curcio Viaggi
Want to know more about travelling around Italy
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Booking & Getting There
Isernia to Pisa bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., arrive at Roma, Autostazione Tiburtina station.
Isernia to Pisa train services, operated by Trenitalia, arrive at Roma Termini station.
Yes, the driving distance between Isernia to Pisa is 507 km. It takes approximately 5h 4m to drive from Isernia to Pisa.
Book your Isernia to Pisa train tickets online with Omio.
Book your Isernia to Pisa bus tickets online with Omio, 12go.asia and FlixBus.
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