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How to get fromLexington to Buffaloby car, plane, bus, or train

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There are 8 ways to get from Lexington to Buffalo by car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Covington, fly to Buffalo Niagara International Airport

    best
    1. Drive from Lexington to Covington (CVG)car car
    2. Fly from Covington (CVG) to Buffalo Niagara International Airport (BUF)plane plane CVG - BUF
    6h 25m
    $169–238

  2. Fly Blue Grass Airport to Buffalo Niagara International Airport

    cheapest
    1. Fly from Blue Grass Airport (LEX) to Buffalo Niagara International Airport (BUF)plane plane LEX - BUF
    7h 56m
    $67–400

  3. Drive, bus

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Wilson & Ferrell Shell Station - Columbusbus bus
    4. Take the bus from Columbus to Buffalobus bus
    20h 11m
    $100–202

  4. Drive, bus, train (Amtrak)

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Chicago Union Stationbus bus
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    22h 35m
    $355–672

  5. Drive  518.7 mi

    1. Drive from Lexington to Buffalocar car 518.7 mi
    8h 55m
    $86–124

  6. Drive to Louisville International Airport, fly to Buffalo Niagara International Airport

    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Buffalo Niagara International Airport (BUF)plane plane SDF - BUF
    6h 40m
    $78–417

  7. Drive to Covington, fly to Toronto Pearson International Airport, bus

    1. Drive from Lexington to Covington (CVG)car car
    2. Fly from Covington (CVG) to Toronto Pearson International Airport (YYZ)plane plane CVG - YYZ
    3. Take the bus from Toronto Pearson Airport to Buffalobus bus
    7h 13m
    $100–505

  8. Drive to Louisville International Airport, fly to Toronto Pearson International Airport, bus

    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Toronto Pearson International Airport (YYZ)plane plane SDF - YYZ
    3. Take the bus from Toronto Pearson Airport to Buffalobus bus
    7h 8m
    $79–364

Covington (CVG) to Buffalo Niagara International Airport (BUF) flights

Calendar75Weekly Planes
Duration5h 28mAverage Duration
Ticket$89Cheapest Price
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Comparing Your Travel Options

Map of how to get from Lexington to Buffalo.ExpandLaunch map view
  • Distance: 500.6 mi
  • Duration: 6h 25m

What companies run services between Lexington, KY, USA and Buffalo, NY, USA?

Delta, United Airlines, and American Airlines fly from Blue Grass Airport (LEX) to Buffalo Niagara International Airport (BUF) hourly.

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