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How to get fromLos Angeles to Defianceby plane, bus, taxi, train (Amtrak), bus (Greyhound, Flixbus, Amtrak), car, or train

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There are 11 ways to get from Los Angeles to Defiance by plane, bus, taxi, train (Amtrak), bus (Greyhound, Flixbus, Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Los Angeles International Airport to Indianapolis, bus, taxi

    best
    1. Fly from Los Angeles International Airport (LAX) to Indianapolis (IND)plane plane LAX - IND
    2. Take the bus from Indianapolis to Fort Waynebus bus
    3. Take the taxi from Fort Wayne to Defiancetaxi taxi
    10h 55m
    $310–567

  2. Fly Los Angeles International Airport to Chicago O'Hare International Airport, train

    cheapest
    1. Fly from Los Angeles International Airport (LAX) to Chicago O'Hare International Airport (ORD)plane plane LAX - ORD
    2. Take the train from Chicago Union Station to Bryan Amtrak Stationtrain train
    11h 15m
    $258–511

  3. Train (Amtrak)

    1. Take the train from Los Angeles to Chicago Union Stationtrain train Southwest Chief / ...
    2. Take the train from Chicago Union Station to Bryan Amtrak Stationtrain train Lake Shore Limited
    2d
    $1,376–2,111

  4. Bus

    1. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Union Station to Bryan Amtrak Stationbus bus
    2d 4h

  5. Drive  2,193 mi

    1. Drive from Los Angeles to Defiancecar car 2,193 mi
    35h 28m
    $363–523

  6. Fly Los Angeles International Airport to Chicago Midway International Airport, train

    1. Fly from Los Angeles International Airport (LAX) to Chicago Midway International Airport (MDW)plane plane LAX - MDW
    2. Take the train from Chicago Union Station to Bryan Amtrak Stationtrain train
    11h 5m
    $320–718

  7. Fly Los Angeles International Airport to John Glenn Columbus International Airport, bus, taxi

    1. Fly from Los Angeles International Airport (LAX) to John Glenn Columbus International Airport (CMH)plane plane LAX - CMH
    2. Take the bus from Wilson & Ferrell Shell Station - Columbus to Delphosbus bus
    3. Take the taxi from Delphos to Defiancetaxi taxi
    11h 14m
    $261–558

  8. Fly Los Angeles International Airport to Detroit, bus, train

    1. Fly from Los Angeles International Airport (LAX) to Detroit (DTW)plane plane LAX - DTW
    2. Take the bus from Dearborn to Toledobus bus
    3. Take the train from Toledo to Bryan Amtrak Stationtrain train
    11h 27m

  9. Fly Los Angeles International Airport to Cleveland-Hopkins International Airport, train

    1. Fly from Los Angeles International Airport (LAX) to Cleveland-Hopkins International Airport (CLE)plane plane LAX - CLE
    2. Take the train from Cleveland Amtrak to Bryan Amtrak Stationtrain train
    11h 52m
    $301–546

  10. Train to John Wayne Airport Orange County, fly to Chicago O'Hare International Airport, train

    1. Take the train from Los Angeles to Anaheimtrain train
    2. Fly from John Wayne Airport Orange County (SNA) to Chicago O'Hare International Airport (ORD)plane plane SNA - ORD
    3. Take the train from Chicago Union Station to Bryan Amtrak Stationtrain train
    12h 58m
    $269–685

  11. Train to John Wayne Airport Orange County, fly to Detroit, bus, train

    1. Take the train from Los Angeles to Anaheimtrain train
    2. Fly from John Wayne Airport Orange County (SNA) to Detroit (DTW)plane plane SNA - DTW
    3. Take the bus from Dearborn to Toledobus bus
    4. Take the train from Toledo to Bryan Amtrak Stationtrain train
    12h 57m

Los Angeles International Airport (LAX) to Indianapolis (IND) flights

Calendar85Weekly Planes
Duration5h 35mAverage Duration
Ticket$130Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Los Angeles to Defiance.ExpandLaunch map view
  • Distance: 2,005.8 mi
  • Duration: 10h 55m

What companies run services between Los Angeles, CA, USA and Defiance, OH, USA?

You can take a train from Los Angeles to Defiance via Chicago Union Station and Bryan Amtrak Station in around 2d. Alternatively, you can take a bus from Los Angeles Union Station to Defiance via St Louis Bus Station, Chicago Bus Station, Chicago Union Station, and Bryan Amtrak Station in around 2d 4h.

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