There are 11 ways to get from Lyon to Palermo by plane, train, ferry, car, car ferry, bus, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Lyon–Saint Exupéry Airport
best- Fly from Lyon–Saint Exupéry Airport (LYS) to Palermo Airport (PMO)plane LYS - PMO
5h 20m€74–331Train to Turin Caselle Airport, fly
cheapest- Take the train from Lyon Part Dieu to Torino Porta Susatrain
- Fly from Turin Caselle Airport (TRN) to Palermo Airport (PMO)plane TRN - PMO
8h 10m€52–207Train, ferry
- Take the train from Lyon Part Dieu to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
- Take the train from Messina Centrale to Palermo Centraletrain Re
19h 52mDrive, car ferry
- Drive from Lyon to Port of Genoacar
- Take the carferry from Port of Genoa to Port of Palermocarferry
24h 18m€185–272Bus, ferry
- Take the bus from Lyon Lyon Perrache Bus Station to Naples Metropark Central Parkingbus Itabus
- Take the ferry from Naples Beverello to Port of Palermoferry
28h 51m€95–185Train to Geneva International Airport, fly
- Take the train from Lyon Part Dieu to Genevetrain
- Fly from Geneva International Airport (GVA) to Palermo Airport (PMO)plane GVA - PMO
7h 15m€96–416Train to Milan Linate Airport, fly
- Take the train from Lyon Part Dieu to Milano Centraletrain
- Fly from Milan Linate Airport (LIN) to Palermo Airport (PMO)plane LIN - PMO
9h 18m€102–270Train, train to Milano Malpensa Airport, fly
- Take the train from Lyon Part Dieu to Milano Centraletrain
- Take the train from Milano Centrale to Malpensa Aeroporto T1train
- Fly from Milano Malpensa Airport (MXP) to Palermo Airport (PMO)plane MXP - PMO
9h 35m€72–343Train
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Roma Terminitrain
- Take the train from Roma Termini to Palermo Centraletrain Ic
20h 35m€213–352Train, car ferry
- Take the train from Lyon Part Dieu to Torino Porta Susatrain Fr
- Take the train from Torino Porta Nuova to Genova P.Za Principetrain
- Take the carferry from Port of Genoa to Port of Palermocarferry
27h 27m€154–240Bus
- Take the bus from Lyon - Gerland Bus Station to Turin - Vittorio Emanuele Bus Stationbus BlaBlaCar Bus
- Take the bus from Turin to Palermobus N597
29h 21m€174–270
Lyon–Saint Exupéry Airport (LYS) to Palermo Airport (PMO) flights
Comparing Your Travel Options
The cheapest way to get from Lyon to Palermo is to train and fly which costs €50 - €210 and takes 8h 10m.
The fastest way to get from Lyon to Palermo is to fly which takes 5h 20m and costs €70 - €340.
No, there is no direct bus from Lyon station to Palermo. However, there are services departing from Lyon - Gerland Bus Station and arriving at Palermo via Turin. The journey, including transfers, takes approximately 29h 21m.
No, there is no direct train from Lyon to Palermo. However, there are services departing from Lyon Part Dieu and arriving at Palermo Centrale via Milano Centrale and Roma Termini. The journey, including transfers, takes approximately 20h 35m.
The distance between Lyon and Palermo is 1120 km.
The best way to get from Lyon to Palermo without a car is to train and ferry which takes 19h 52m and costs .
It takes approximately 5h 20m to get from Lyon to Palermo, including transfers.
Lyon to Palermo bus services, operated by BlaBlaCar Bus, depart from Lyon - Gerland Bus Station.
Lyon to Palermo train services, operated by Trenitalia, depart from Lyon Part Dieu station.
The best way to get from Lyon to Palermo is to fly which takes 5h 20m and costs €70 - €340. Alternatively, you can train, which costs €210 - €360 and takes 20h 35m, you could also bus, which costs €170 - €270 and takes 29h 21m.
What companies run services between Lyon, France and Palermo, Italy?
Volotea, easyJet, and Transavia France fly from Lyon–Saint Exupéry Airport (LYS) to Palermo Airport (PMO) 3 times a week. Alternatively, you can take a train from Lyon Part Dieu to Palermo Centrale via Milano Centrale and Roma Termini in around 20h 35m.
- Website
- ryanair.com
Flights from Turin Caselle Airport to Palermo Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €25–95
Flights from Milano Malpensa Airport to Palermo Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €40–120
- Website
- easyjet.com
Flights from Lyon–Saint Exupéry Airport to Palermo Airport
- Ave. Duration
- 1h 50m
- When
- Thursday
- Estimated price
- €70–340
Flights from Geneva International Airport to Palermo Airport
- Ave. Duration
- 1h 50m
- When
- Saturday
- Estimated price
- €50–310
Flights from Milano Malpensa Airport to Palermo Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- €9–290
- Website
- ita-airways.com
Flights from Turin Caselle Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- €70–170
Flights from Geneva International Airport to Palermo Airport via Rome
- Ave. Duration
- 4h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €110–290
Flights from Milan Linate Airport to Palermo Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €45–150
Flights from Milan Linate Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- €45–150
- Website
- volotea.com
Flights from Lyon–Saint Exupéry Airport to Palermo Airport
- Ave. Duration
- 1h 55m
- When
- Friday
- Estimated price
- €28–250
Flights from Turin Caselle Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- €70–170
Flights from Geneva International Airport to Palermo Airport via Rome
- Ave. Duration
- 4h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €110–290
Flights from Milan Linate Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- €45–150
- Website
- flyulendo.com
Flights from Turin Caselle Airport to Palermo Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €10–75
Flights from Turin Caselle Airport to Palermo Airport via Rome
- Ave. Duration
- 3h 50m
- When
- Wednesday
- Estimated price
- €10–75
Flights from Milano Malpensa Airport to Palermo Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €9–290
- Website
- transavia.com
Flights from Lyon–Saint Exupéry Airport to Palermo Airport
- Ave. Duration
- 2h
- When
- Thursday
- Estimated price
- €45–270
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- 4 times a day
- Estimated price
- €35–50
- Website
- Trenitalia
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- €26–40
- Website
- Trenitalia
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- 4 times a day
- Estimated price
- €35–50
- Website
- Trenitalia
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- 4 times a day
- Estimated price
- €50–75
- Website
- Trenitalia
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- 4 times a day
- Estimated price
- €50–75
- Website
- Trenitalia
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- 4 times a day
- Estimated price
- €50–75
- Website
- Trenitalia
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- 4 times a day
- Estimated price
- €35–50
- Website
- Trenitalia
Train from Torino Porta Nuova to Genova P.Za Principe
- Ave. Duration
- 2h 6m
- Frequency
- Hourly
- Estimated price
- €19–26
- Website
- Trenitalia
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Torino Porta Susa to Villa S.Giovanni
- Ave. Duration
- 10h 30m
- Frequency
- 5 times a day
- Estimated price
- €180–310
- Website
- Trenitalia Frecce
Train from Torino Porta Nuova to Genova P.Za Principe
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- €22–40
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Torino Porta Susa to Villa S.Giovanni
- Ave. Duration
- 11h 37m
- Frequency
- Once daily
- Estimated price
- €150–260
- Website
- Italo Treno
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €65–110
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Messina Centrale to Palermo Centrale
- Ave. Duration
- 3h 3m
- Frequency
- 4 times a day
- Estimated price
- €24–45
- Website
- Trenitalia Intercity
Train from Roma Termini to Palermo Centrale
- Ave. Duration
- 11h 32m
- Frequency
- 4 times a day
- Estimated price
- €95–170
- Website
- Trenitalia Intercity
Train from Torino Porta Nuova to Genova P.Za Principe
- Ave. Duration
- 1h 41m
- Frequency
- Every 4 hours
- Estimated price
- €17–35
- Website
- Trenitalia Intercity
- Phone
- +33 1 84 94 36 35
- Website
- Oui.SNCF
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 2h 2m
- Frequency
- Hourly
- Estimated price
- €30–50
- Website
- Oui.SNCF
- Phone
- +33 1 84 94 36 35
- Website
- TGV inOui
Train from Lyon Part Dieu to Geneve
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- €30–45
- Website
- TGV inOui
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- Trenord
Train from Milano Centrale to Malpensa Aeroporto T1
- Ave. Duration
- 53 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- Trenord
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Lyon Lyon Perrache Bus Station to Naples Metropark Central Parking
- Ave. Duration
- 18h 45m
- Frequency
- Once daily
- Estimated price
- €60–120
- Website
- Itabus S.p.A.
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Lyon - Gerland Bus Station to Turin - Vittorio Emanuele Bus Station
- Ave. Duration
- 4h 16m
- Frequency
- Every 2 hours
- Estimated price
- €24–45
- Website
- BlaBlaCar Bus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Lyon - Gerland Bus Station to Turin - Vittorio Emanuele Bus Station
- Ave. Duration
- 5h 15m
- Frequency
- Hourly
- Estimated price
- €27–40
- Website
- Flixbus
Bus from Turin to Palermo
- Ave. Duration
- 24h 5m
- Frequency
- Once daily
- Estimated price
- €150–230
- Website
- Flixbus
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
- Phone
- +39 010 209 4591
- [email protected]
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 19h 30m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
Car ferry from Port of Genoa to Port of Palermo
- Ave. Duration
- 19h 30m
- Frequency
- Once daily
- Estimated price
- €100–150
- Website
- Grandi Navi Veloci
- Phone
- +39.081.496.444
- [email protected]
- Website
- Grimaldi Lines
Ferry from Naples Beverello to Port of Palermo
- Ave. Duration
- 8h 32m
- Frequency
- 6 times a week
- Estimated price
- €30–70
- Website
- Grimaldi Lines
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Lyon to Palermo bus services, operated by BlaBlaCar Bus, arrive at Turin - Vittorio Emanuele Bus Station.
Lyon to Palermo train services, operated by Trenitalia, arrive at Milano Centrale station.
Book your Lyon to Palermo train tickets online with Omio.
Book your Lyon to Palermo bus tickets online with Omio, 12go.asia and FlixBus.
There are 6050+ hotels available in Palermo.


























































