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How to get fromMainz to Brnoby plane, train, bus, or car

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There are 11 ways to get from Mainz to Brno by plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Frankfurt to Vienna International Airport, train

    best
    1. Fly from Frankfurt (FRA) to Vienna International Airport (VIE)plane plane FRA - VIE
    2. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    6h
    Kč 1,906–5,204

  2. Bus via Prague

    cheapest
    1. Take the bus from Frankfurt Central Train Station to Prague Florenc Central Bus Stationbus bus : Amsterdam Central Sloterdijk Train Station - Prague Central Bus Station / ...
    2. Take the bus from Praha, ÚAN Florenc to Brnobus bus 850 / ...
    11h 24m
    Kč 1,222–2,121

  3. Train via Munich

    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train 55 / ...
    2. Take the train from Mannheim, Hauptbahnhof to München Hbftrain train 11 / ...
    3. Take the train from Muenchen Hbf Gl.5-10 to Salzburg Hbftrain train Re / ...
    4. Take the train from Salzburg Hbf to Wien Hbftrain train Rjx / ...
    5. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train Rj / ...
    10h 16m
    Kč 2,678–7,451

  4. Drive  743.6 km

    1. Drive from Mainz to Brnocar car 743.6 km
    6h 12m
    Kč 3,256–4,703

  5. Fly Frankfurt to Václav Havel Airport Prague, train

    1. Fly from Frankfurt (FRA) to Václav Havel Airport Prague (PRG)plane plane FRA - PRG
    2. Take the train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazitrain train
    6h 53m
    Kč 1,739–4,784

  6. Train to Stuttgart Airport, fly to Vienna International Airport, train

    1. Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain train
    2. Fly from Stuttgart Airport (STR) to Vienna International Airport (VIE)plane plane STR - VIE
    3. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    7h 50m
    Kč 2,667–8,155

  7. Fly Frankfurt to Dresden Airport, train

    1. Fly from Frankfurt (FRA) to Dresden Airport (DRS)plane plane FRA - DRS
    2. Take the train from Dresden-Neustadt to Brno hl.n.train train
    9h 6m
    Kč 3,643–8,296

  8. Train to Cologne Bonn Airport, fly to Vienna International Airport, train

    1. Take the train from Frankfurt to Siegburg Bftrain train
    2. Fly from Cologne Bonn Airport (CGN) to Vienna International Airport (VIE)plane plane CGN - VIE
    3. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    7h 48m
    Kč 2,056–8,324

  9. Fly Frankfurt to Linz Airport, train

    1. Fly from Frankfurt (FRA) to Linz Airport (LNZ)plane plane FRA - LNZ
    2. Take the train from Linz/Donau Hbf to Wien Hbftrain train
    3. Take the train from Wien Hbf to Brno Hlavni Nadrazitrain train
    8h 8m
    Kč 3,073–6,666

  10. Train

    1. Take the train from Frankfurt to Praha Hlavní nádražítrain train Drf
    2. Take the train from Praha Hlavni Nadrazi to Brno Hlavni Nadrazitrain train Rj / ...
    14h 38m

  11. Bus

    1. Take the bus from Frankfurt, Hauptbahnhof FOB to Brno Hlavní Nádražíbus bus Ivano-Frankivsk
    20h 59m
    Kč 3,445–4,052

Mainz to Brno by train

Calendar185Weekly Trains
Duration10h 16mAverage Duration
TicketKč 2,678Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mainz to Brno.ExpandLaunch map view
  • Distance: 812 km
  • Duration: 6h

What companies run services between Mainz, Germany and Brno, Czechia?

You can take a train from Mainz, Hauptbahnhof to Brno Hlavni Nadrazi via Mannheim, Hauptbahnhof, München Hbf, Muenchen Hbf Gl.5-10, Salzburg Hbf, and Wien Hbf in around 10h 16m. Alternatively, you can take a bus from Mainz central train station to Brno via Frankfurt Central Train Station and Praha, ÚAN Florenc in around 11h 24m.

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