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How to get fromMainz to Lyonby plane, train (TGV), train, bus, or car

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There are 6 ways to get from Mainz to Lyon by plane, train (TGV), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Frankfurt

    best
    1. Fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS)plane plane FRA - LYS
    4h 29m
    €130–348
  2. Train, bus

    cheapest
    1. Take the train from Mainz, Hauptbahnhof to Saarbrücken Hbftrain train Re3 / ...
    2. Take the bus from Saarbrücken bus station to Lyonbus bus N235
    10h 45m
    €74–111
  3. Train

    1. Take the train from Mainz, Hauptbahnhof to Karlsruhe Hauptbahnhoftrain train Re4
    2. Take the train from Karlsruhe Hauptbahnhof to Strasbourg Bahnhoftrain train 83 / ...
    3. Take the train from Strasbourg to Lyon Part Dieutrain train Tgv
    8h 35m
    €130–216
  4. Drive  652.8 km

    1. Drive from Mainz to Lyoncar car 652.8 km
    6h 2m
    €120–173
  5. Train to Düsseldorf International Airport, fly

    1. Take the train from Mainz Hbf to Duesseldorf Hbftrain train
    2. Fly from Düsseldorf International Airport (DUS) to Lyon–Saint Exupéry Airport (LYS)plane plane DUS - LYS
    6h 55m
    €133–353
  6. Bus

    1. Take the bus from FRANKFURT AM MAIN, Hbf Südseite - Pforzheimer Str. to LYON, Lyon - Perrache - poziom górny Abus bus
    11h 55m
    €99–101

Mainz to Lyon by train

Calendar63Weekly Trains
Duration8h 35mAverage Duration
Ticket€130Cheapest Price
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Comparing Your Travel Options

What companies run services between Mainz, Germany and Lyon, France?

Lufthansa, Airbus France, and three other airlines fly from Frankfurt (FRA) to Lyon–Saint Exupéry Airport (LYS) every 4 hours. Alternatively, you can take a train from Mainz, Hauptbahnhof to Lyon Part Dieu via Karlsruhe Hauptbahnhof, Strasbourg Bahnhof, and Strasbourg in around 8h 35m.

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