There are 9 ways to get from Mainz to Pisa by plane, train, train (Trenitalia), bus, car, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Peretola Airport, train
best- Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane FRA - FLR
- Take the train from Firenze S.M.N. to Pisa Centraletrain
5h 48m€135–347Bus via Milan
cheapest- Take the bus from Mainz central train station to Milanbus FlixBus 476
- Take the bus from Milan to Pisabus FlixBus 507
19h 35m€101–152Train
- Take the train from Frankfurt to Basel SBBtrain 43
- Take the train from Basel SBB to Luganotrain Ec
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Pisa Centraletrain Re
13h 31m€138–365Bus
- Take the bus from Wiesbaden Gartenfeldstraße P+R to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Pisabus 443 / ...
18h 57m€142–207Drive 941.9 km
- Drive from Mainz to Pisacar 941.9 km
9h 4m€170–245Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane FRA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Pisa Centraletrain
6h 16m€118–306Fly to Pisa International Airport
- Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane FRA - PSA
3h 58m€104–292Fly to Venice Marco Polo Airport, train
- Fly from Frankfurt (FRA) to Venice Marco Polo Airport (VCE)plane FRA - VCE
- Take the train from Venezia Mestre to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Pisa Centraletrain
8h 2m€135–317Night train, train
- Take the nighttrain from Mainz Hbf to Zuerich Hbnighttrain Nj
- Take the train from Zürich HB to Luganotrain Ec / ...
- Take the train from Lugano to Milano Centraletrain
- Take the train from Milano Centrale to Pisa Centraletrain Ic
15h 52m€142–300
Mainz to Pisa by train
Comparing Your Travel Options
The cheapest way to get from Mainz to Pisa is to bus via Milan which costs €100 - €160 and takes 19h 35m.
The fastest way to get from Mainz to Pisa is to fly which takes 3h 58m and costs €100 - €300.
No, there is no direct bus from Mainz to Pisa. However, there are services departing from Wiesbaden-Mainz-Kastel Bahnhof and arriving at Pisa via Wiesbaden Gartenfeldstraße P+R and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 18h 57m.
No, there is no direct train from Mainz to Pisa. However, there are services departing from Mainz, Römisches Theater and arriving at Pisa Centrale via Frankfurt, Basel SBB, Lugano, Milano Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 13h 31m.
The distance between Mainz and Pisa is 832 km. The road distance is 941.9 km.
The best way to get from Mainz to Pisa without a car is to train which takes 13h 31m and costs €130 - €370.
It takes approximately 5h 48m to get from Mainz to Pisa, including transfers.
Mainz to Pisa bus services, operated by Onebus, depart from Wiesbaden Gartenfeldstraße P+R station.
Mainz to Pisa train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
The best way to get from Mainz to Pisa is to train which takes 13h 31m and costs €130 - €370. Alternatively, you can bus, which costs €140 - €210 and takes 18h 57m, you could also fly, which costs €100 - €300 and takes 3h 58m.
What companies run services between Mainz, Germany and Pisa, Italy?
You can take a train from Mainz, Römisches Theater to Pisa Centrale via Frankfurt, Basel SBB, Lugano, Milano Centrale, and Firenze S.M.N. in around 13h 31m. Alternatively, you can take a bus from Wiesbaden-Mainz-Kastel Bahnhof to Pisa via Wiesbaden Hauptbahnhof, Wiesbaden Gartenfeldstraße P+R, and Florence Villa Constanza Bus Station in around 18h 57m.
- Website
- lufthansa.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- €100–550
Flights from Frankfurt to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 6m
- When
- Every day
- Estimated price
- €170–600
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €95–480
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €95–480
Flights from Frankfurt to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Saturday and Sunday
- Estimated price
- €150–500
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €85–250
Flights from Frankfurt to Venice Marco Polo Airport via Munich
- Ave. Duration
- 3h 8m
- When
- Every day
- Estimated price
- €140–450
- Website
- airdolomiti.it
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €170–550
Flights from Frankfurt to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €150–480
Flights from Frankfurt to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Saturday and Sunday
- Estimated price
- €150–500
- Website
- condor.com
Flights from Frankfurt to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €130–340
Flights from Frankfurt to Venice Marco Polo Airport
- Ave. Duration
- 1h 20m
- When
- Friday
- Estimated price
- €85–210
- Website
- swiss.com
Flights from Frankfurt to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 10m
- When
- Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €85–340
Flights from Frankfurt to Bologna Guglielmo Marconi Airport via Zurich
- Ave. Duration
- 3h 20m
- When
- Monday and Saturday
- Estimated price
- €75–290
- Website
- austrian.com
Flights from Frankfurt to Venice Marco Polo Airport via Vienna
- Ave. Duration
- 3h 25m
- When
- Monday and Wednesday
- Estimated price
- €70–300
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 21m
- Frequency
- Every 15 minutes
- Estimated price
- €9–13
- Website
- Trenitalia
Train from Milano Centrale to Pisa Centrale
- Ave. Duration
- 4h 55m
- Frequency
- 4 times a week
- Estimated price
- €35–50
- Website
- Trenitalia
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Basel SBB
- Ave. Duration
- 2h 57m
- Frequency
- Hourly
- Estimated price
- €50–100
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Basel SBB to Lugano
- Ave. Duration
- 2h 54m
- Frequency
- Every 3 hours
- Estimated price
- €80–130
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €25–40
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Zürich HB to Lugano
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €55–90
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Lugano to Milano Centrale
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €25–40
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +49 (0) 7531 915109
- [email protected]
- Website
- SBB GmbH
Train from Basel SBB to Lugano
- Ave. Duration
- 3h 21m
- Frequency
- Once daily
- Estimated price
- €20–25
- Schedules at
- SBB GmbH
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €40–70
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 38 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–21
- Website
- Trenitalia Frecce
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €30–60
- Website
- Trenitalia Frecce
Train from Milano Centrale to Pisa Centrale
- Ave. Duration
- 3h 54m
- Frequency
- Twice daily
- Estimated price
- €40–70
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 2h 3m
- Frequency
- Twice daily
- Estimated price
- €35–60
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 38 min
- Frequency
- Twice daily
- Estimated price
- €10–18
- Website
- Italo Treno
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 11m
- Frequency
- Once daily
- Estimated price
- €28–50
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Twice daily
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €10–18
- Website
- Trenitalia Intercity
Train from Milano Centrale to Pisa Centrale
- Ave. Duration
- 4h 12m
- Frequency
- Every 2 hours
- Estimated price
- €30–60
- Website
- Trenitalia Intercity
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Night train from Mainz Hbf to Zuerich Hb
- Ave. Duration
- 6h 22m
- Frequency
- Twice daily
- Estimated price
- €50–95
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +43 (0) 51717
- Website
- Nightjet
Night train from Mainz Hbf to Zuerich Hb
- Ave. Duration
- 6h 22m
- Frequency
- 6 times a week
- Estimated price
- €30–101
- Website
- Nightjet
- Sleeper Carriage
- €97–101
- Couchette Carriage
- €60–75
- Seating Carriage
- €30–40
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from Wiesbaden Gartenfeldstraße P+R to Florence Villa Constanza Bus Station
- Ave. Duration
- 15h 2m
- Frequency
- Once a week
- Estimated price
- €130–190
- Website
- Onebus
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Florence Villa Constanza Bus Station to Pisa
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Website
- Flixbus
Bus from Mainz central train station to Milan
- Ave. Duration
- 12h 5m
- Frequency
- Once daily
- Estimated price
- €65–100
- Website
- Flixbus
Bus from Milan to Pisa
- Ave. Duration
- 6h 30m
- Frequency
- Twice daily
- Estimated price
- €35–55
- Website
- Flixbus
Want to know more about travelling around Italy
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Booking & Getting There
Mainz to Pisa bus services, operated by Onebus, arrive at Florence Villa Constanza Bus Station.
Mainz to Pisa train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Basel SBB station.
Yes, the driving distance between Mainz to Pisa is 942 km. It takes approximately 9h 4m to drive from Mainz to Pisa.
Book your Mainz to Pisa train tickets online with Omio.
Book your Mainz to Pisa bus tickets online with Omio.
There are 4432+ hotels available in Pisa.

















































