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How to get fromMainz to Tuscanyby plane, train (Trenitalia), bus, night train, train, or car

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There are 8 ways to get from Mainz to Tuscany by plane, train (Trenitalia), bus, night train, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Peretola Airport

    best
    1. Fly from Frankfurt (FRA) to Florence Peretola Airport (FLR)plane plane FRA - FLR
    4h 18m
    €126–334

  2. Bus via Frankfurt am Main

    cheapest
    1. Take the bus from Frankfurt central train station to Florence Villa Constanza Bus Stationbus bus N77 / ...
    18h 49m
    €98–156

  3. Train

    1. Take the train from Frankfurt to Basel SBBtrain train 43
    2. Take the train from Basel SBB to Luganotrain train Ec
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    12h 3m
    €129–352

  4. Bus

    1. Take the bus from Wiesbaden Gartenfeldstraße P+R to Florence Villa Constanza Bus Stationbus bus
    16h 43m
    €136–196

  5. Night train, train

    1. Take the nighttrain from Mainz Hbf to Zuerich Hbnighttrain night train Nj
    2. Take the train from Zürich HB to Luganotrain train Ec / ...
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    13h 5m
    €142–300

  6. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Frankfurt (FRA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FRA - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4h 48m
    €109–293

  7. Fly to Pisa International Airport

    1. Fly from Frankfurt (FRA) to Pisa International Airport (PSA)plane plane FRA - PSA
    3h 58m
    €104–292

  8. Drive  957.9 km

    1. Drive from Mainz to Florencecar car 957.9 km
    9h 3m
    €173–249

Mainz to Tuscany by train

Calendar76Weekly Trains
Duration12h 3mAverage Duration
Ticket€129Cheapest Price
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Comparing Your Travel Options

Map of how to get from Mainz to Tuscany.ExpandLaunch map view
  • Distance: 753.8 km
  • Duration: 4h 18m

What companies run services between Mainz, Germany and Tuscany, Italy?

Lufthansa, Condor Flugdienst, and two other airlines fly from Frankfurt (FRA) to Florence Peretola Airport (FLR) every 3 hours. Alternatively, you can take a train from Mainz, Römisches Theater to Firenze S.M.N. via Frankfurt, Basel SBB, Lugano, and Milano Centrale in around 12h 3m.

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