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How to get fromMurrells Inlet to Jacksonvilleby car, train, bus (Greyhound), plane, or bus

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There are 5 ways to get from Murrells Inlet to Jacksonville by car, train, bus (Greyhound), plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, train (Amtrak)

    best
    1. Drive from Murrells Inlet to Kingstree Stationcar car
    2. Take the train from Kingstree Station to Jacksonvilletrain train Silver Meteor
    7h 11m
    $183–292

  2. Drive  318.3 mi

    cheapest
    1. Drive from Murrells Inlet to Jacksonvillecar car 318.3 mi
    5h 56m
    $53–76

  3. Bus (Greyhound)

    1. Take the bus from Myrtle Beach Bus Station to Camdenbus bus Greyhound US0641S
    2. Take the bus from Camden to Jacksonvillebus bus Greyhound US0644S
    12h 6m
    $124–176

  4. Fly

    1. Fly from Myrtle Beach (MYR) to Jacksonville (JAX)plane plane MYR - JAX
    5h 41m
    $107–451

  5. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Charleston Bus Stationbus bus Greyhound US0641S / ...
    2. Take the train from Charleston Amtrak Station to Jacksonvilletrain train Silver Meteor
    8h 24m
    $203–305

Myrtle Beach (MYR) to Jacksonville (JAX) flights

Calendar69Weekly Planes
Duration4h 44mAverage Duration
Ticket$67Cheapest Price
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Comparing Your Travel Options

Map of how to get from Murrells Inlet to Jacksonville.ExpandLaunch map view
  • Distance: 372.7 mi
  • Duration: 7h 11m

What companies run services between Murrells Inlet, SC, USA and Jacksonville, FL, USA?

You can take a vehicle from Murrells Inlet to Jacksonville via Myrtle Beach Bus Station and Camden in around 12h 6m. Alternatively, Delta, American Airlines, and Southwest Airlines fly from Myrtle Beach (MYR) to Jacksonville (JAX) every 3 hours.

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Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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