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How to get fromMyrtle Beach to Indianaby plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

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There are 7 ways to get from Myrtle Beach to Indiana by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Indianapolis

    best
    1. Fly from Myrtle Beach (MYR) to Indianapolis (IND)plane plane MYR - IND
    2h 58m
    $99–516

  2. Fly to Chicago O'Hare International Airport, train

    cheapest
    1. Fly from Myrtle Beach (MYR) to Chicago O'Hare International Airport (ORD)plane plane MYR - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    4h 45m
    $77–319

  3. Bus via Atlanta

    1. Take the bus from Myrtle Beach Bus Station to Atlanta Bus Stationbus bus Greyhound US0641S
    2. Take the bus from Atlanta Bus Station to Indianapolisbus bus FlixBus 2512
    21h 35m
    $156–237

  4. Bus, train

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the train from Fayetteville Amtrak Station to Richmond Staples Mill Road Amtrak Stationtrain train
    3. Take the bus from Richmond Staples Mill Road Station to Charlottesville Amtrak Stationbus bus
    4. Take the train from Charlottesville to Indianapolistrain train
    27h 8m

  5. Drive  718.7 mi

    1. Drive from Myrtle Beach to Indianapoliscar car 718.7 mi
    13h 27m
    $119–172

  6. Fly to Evansville

    1. Fly from Myrtle Beach (MYR) to Evansville (EVV)plane plane MYR - EVV
    4h 40m
    $91–387

  7. Bus

    1. Take the bus from Myrtle Beach Bus Station to Fayetteville Bus Stationbus bus
    2. Take the bus from Fayetteville to Winston-Salembus bus
    3. Take the bus from Winston Salem to Columbusbus bus
    4. Take the bus from Columbus to Indianapolis Union Stationbus bus
    23h 30m
    $122–216

Myrtle Beach to Indiana by bus

Calendar7Weekly Buses
Duration21h 35mAverage Duration
Ticket$156Cheapest Price
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Comparing Your Travel Options

Map of how to get from Myrtle Beach to Indiana.ExpandLaunch map view
  • Distance: 599.6 mi
  • Duration: 2h 58m

What companies run services between Myrtle Beach, SC, USA and Indiana, USA?

Southwest Airlines, American Airlines, and Delta fly from Myrtle Beach (MYR) to Indianapolis (IND) 5 times a day. Alternatively, you can take a bus from Myrtle Beach Bus Station to Indianapolis via Atlanta Bus Station in around 21h 35m.

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Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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Need to know: Greyhound

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