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How to get fromNaples to Sistine Chapelby train (Trenitalia), bus, car, or train

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There are 4 ways to get from Naples to Sistine Chapel by train (Trenitalia), bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Napoli Centrale to Roma Terminitrain train Fr
    1h 46m
    €26–51
  2. Bus, line 62 bus

    cheapest
    1. Take the bus from Napoli P.zza Garibaldi to Roma, Autostazione Tiburtinabus bus 538 / ...
    2. Take the bus from Roma, Autostazione Tiburtina to Cavalleggeri/S. Pietrobus bus 62
    3h 49m
    €20–37
  3. Drive  221.7 km

    1. Drive from Naples to Sistine Chapelcar car 221.7 km
    2h 20m
    €40–58
  4. Train, line 64 bus

    1. Take the train from Napoli Centrale to Roma Terminitrain train 9962
    2. Take the bus from Termini to Cavalleggeri/S. Pietrobus bus 64 / ...
    2h 18m
    €27–51

Naples to Sistine Chapel by bus and foot

Calendar172Weekly Services
Duration3h 49mAverage Duration
Ticket€20Cheapest Price
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Comparing Your Travel Options

What companies run services between Naples, Italy and Sistine Chapel, Vatican City?

Trenitalia Frecce operates a train from Napoli Centrale to Roma Termini every 20 minutes. Tickets cost €29–50 and the journey takes 1h 10m. Three other operators also service this route. Alternatively, you can take a bus from Napoli P.zza Garibaldi to Sistine Chapel via Roma, Autostazione Tiburtina and Cavalleggeri/S. Pietro in around 3h 49m.

Train operators
Bus operators

Want to know more about travelling around Vatican City

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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