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How to get fromPisa to Santanderby plane, bus, train, or car

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There are 11 ways to get from Pisa to Santander by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Pisa International Airport to Bilbao Airport, bus

    best
    1. Fly from Pisa International Airport (PSA) to Bilbao Airport (BIO)plane plane PSA - BIO
    2. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    7h 14m
    €62–242

  2. Train, bus via Madrid

    1. Take the train from Pisa Centrale to Genova P.Za Principetrain train Fr / ...
    2. Take the bus from Genoa to Marseille, Gare de Marseille-Saint-Charlesbus bus 798 / ...
    3. Take the train from Marseille St Charles to Madrid-Puerta de Atocha-Almudena Grandestrain train
    4. Take the train from Madrid Chamartín to Santandertrain train Alv / ...
    22h 30m
    €239–379

  3. Bus

    1. Take the bus from Pisa to Nice Airportbus bus
    2. Take the bus from Nice Airport to Bilbaobus bus
    3. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    25h 14m
    €136–211

  4. Drive  1,431.8 km

    1. Drive from Pisa to Santandercar car 1,431.8 km
    14h 5m
    €258–372

  5. Train to Florence Peretola Airport, fly to Santander Airport

    1. Take the train from Pisa Centrale to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Santander Airport (SDR)plane plane FLR - SDR
    9h 15m
    €76–325

  6. Fly Pisa International Airport to Santander Airport

    1. Fly from Pisa International Airport (PSA) to Santander Airport (SDR)plane plane PSA - SDR
    4h 45m
    €75–320

  7. Train, train to Bologna Guglielmo Marconi Airport, fly to Santander Airport

    1. Take the train from Pisa Centrale to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Santander Airport (SDR)plane plane BLQ - SDR
    6h 42m
    €74–293

  8. Fly Pisa International Airport to Adolfo Suárez Madrid–Barajas Airport, train

    1. Fly from Pisa International Airport (PSA) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane PSA - MAD
    2. Take the train from Madrid Chamartín to Santandertrain train
    7h 49m
    €73–314

  9. Train to Florence Peretola Airport, fly to Bilbao Airport, bus

    1. Take the train from Pisa Centrale to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Bilbao Airport (BIO)plane plane FLR - BIO
    3. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    8h 49m
    €95–271

  10. Train, bus

    1. Take the train from Pisa Centrale to Ventimigliatrain train Ic
    2. Take the train from Ventimiglia to Nice Saint-Augustintrain train C3
    3. Take the bus from Nice Airport to Bilbaobus bus
    4. Take the bus from Bilbao Intermodal to Estación de autobuses de Santanderbus bus
    25h 41m
    €149–238

  11. Train, bus #2

    1. Take the train from Pisa Centrale to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Padovatrain train Fr
    3. Take the bus from Padova to Estación de autobuses de Santanderbus bus
    29h 8m
    €158–213

Pisa to Santander by train and bus

Calendar14Weekly Services
Duration22h 30mAverage Duration
Ticket€239Cheapest Price
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Comparing Your Travel Options

Map of how to get from Pisa to Santander.ExpandLaunch map view
  • Distance: 1,185.8 km
  • Duration: 7h 14m

What companies run services between Pisa, Italy and Santander, Spain?

You can take a bus from Pisa to Estación de autobuses de Santander via Nice Airport, Bilbao, and Bilbao Intermodal in around 25h 14m. Alternatively, Ryanair, Volotea, and Iberia fly from Pisa International Airport (PSA) to Santander Airport (SDR) 4 times a week.

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Want to know more about travelling around Spain

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