There are 5 ways to get from Portland to Louisville by plane, bus (Flixbus, Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Louisville International Airport
best- Fly from Portland International Airport (PDX) to Louisville International Airport (SDF)plane PDX - SDF
8h 46m$204–906Fly to Blue Grass Airport, drive
cheapest- Fly from Portland International Airport (PDX) to Blue Grass Airport (LEX)plane PDX - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
8h 35m$134–571Bus
- Take the bus from Portland Curbside Bus Stop to Pasco Bus Stopbus
- Take the bus from Pasco Bus Stop to Denver Union Stationbus
- Take the bus from Denver Union Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Evansville Bus Stationbus
- Take the bus from Evansville, IN to Louisville, KYbus
2d 5h$448–765Train, bus (Amtrak)
- Take the train from Portland to Chicago Union Stationtrain Empire Builder
- Take the bus from Chicago Union Station to Louisville, KYbus Chicago
2d 5h$1,284–1,953Drive 2,284 mi
- Drive from Portland to Louisvillecar 2,284 mi
36h 26m$378–545
Portland to Louisville by bus
Comparing Your Travel Options
The cheapest way to get from Portland to Louisville is to fly and drive which costs $130 - $600 and takes 8h 35m.
The fastest way to get from Portland to Louisville is to fly and drive which takes 8h 35m and costs $130 - $600.
No, there is no direct bus from Portland to Louisville. However, there are services departing from Portland Curbside Bus Stop and arriving at Louisville, KY via Pasco Bus Stop, Denver Union Station, St Louis Bus Station and Evansville, IN. The journey, including transfers, takes approximately 2 days 5h.
The distance between Portland and Louisville is 1973 miles. The road distance is 2297.4 miles.
The best way to get from Portland to Louisville without a car is to bus which takes 2 days 5h and costs $440 - $800.
It takes approximately 8h 46m to get from Portland to Louisville, including transfers.
Portland to Louisville bus services, operated by Flixbus USA, depart from Portland Curbside Bus Stop station.
The best way to get from Portland to Louisville is to fly which takes 8h 46m and costs $200 - $950. Alternatively, you can bus, which costs $440 - $800 and takes 2 days 5h.
Portland to Louisville bus services, operated by Flixbus USA, arrive at Pasco Bus Stop station.
Louisville is 3h ahead of Portland. It is currently 4:51 AM in Portland and 7:51 AM in Louisville.
What companies run services between Portland, OR, USA and Louisville, KY, USA?
Southwest Airlines, United Airlines, and three other airlines fly from Portland International Airport (PDX) to Louisville International Airport (SDF) hourly. Alternatively, you can take a bus from Portland Curbside Bus Stop to Louisville, KY via Pasco Bus Stop, Denver Union Station, St Louis Bus Station, and Evansville, IN in around 2d 5h.
- Website
- united.com
Flights from Portland International Airport to Louisville International Airport via Denver
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $200–900
Flights from Portland International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 7h 3m
- When
- Every day
- Estimated price
- $200–900
Flights from Portland International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 7h 5m
- When
- Every day
- Estimated price
- $120–550
Flights from Portland International Airport to Blue Grass Airport via Denver
- Ave. Duration
- 6h 21m
- When
- Every day
- Estimated price
- $120–550
- Website
- delta.com
Flights from Portland International Airport to Louisville International Airport via Minneapolis
- Ave. Duration
- 7h 55m
- When
- Every day
- Estimated price
- $200–900
Flights from Portland International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 7h 40m
- When
- Every day
- Estimated price
- $220–950
Flights from Portland International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 7h 54m
- When
- Every day
- Estimated price
- $140–600
Flights from Portland International Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 7h 33m
- When
- Every day
- Estimated price
- $130–550
- Website
- aa.com
Flights from Portland International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 7h 17m
- When
- Every day
- Estimated price
- $200–900
Flights from Portland International Airport to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 17m
- When
- Every day
- Estimated price
- $130–600
Flights from Portland International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 8h 2m
- When
- Every day
- Estimated price
- $120–550
Flights from Portland International Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 7h 43m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $140–600
- Website
- southwest.com
Flights from Portland International Airport to Louisville International Airport via Denver
- Ave. Duration
- 6h 5m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $200–900
Flights from Portland International Airport to Louisville International Airport via Chicago Midway
- Ave. Duration
- 6h 38m
- When
- Monday, Thursday, Tuesday, Wednesday, and Sunday
- Estimated price
- $200–900
Flights from Portland International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 6h 45m
- When
- Monday and Thursday
- Estimated price
- $210–950
- Website
- alaskaair.com
Flights from Portland International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 7h 12m
- When
- Every day
- Estimated price
- $300–1,300
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Portland to Chicago Union Station
- Ave. Duration
- 46h
- Frequency
- Once daily
- Estimated price
- $1,200–1,900
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Portland Curbside Bus Stop to Pasco Bus Stop
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $30–50
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Pasco Bus Stop to Denver Union Station
- Ave. Duration
- 22h 40m
- Frequency
- Once daily
- Estimated price
- $200–310
- Website
- Greyhound
Bus from Denver Union Station to St Louis Bus Station
- Ave. Duration
- 16h 45m
- Frequency
- Twice daily
- Estimated price
- $150–230
- Website
- Greyhound
Bus from St Louis Bus Station to Evansville Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Estimated price
- $29–45
- Website
- Greyhound
- Phone
- +1 502-368-5644 x 135
- Website
- Miller Transportation
Bus from Evansville, IN to Louisville, KY
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $35–130
- Website
- Miller Transportation
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Chicago Union Station to Louisville, KY
- Ave. Duration
- 6h 45m
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- Amtrak
- Adult
- $50–60
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Booking & Getting There
Yes, the driving distance between Portland to Louisville is 2297 miles. It takes approximately 36h 26m to drive from Portland to Louisville.
Book your Portland to Louisville bus tickets online with Omio.
There are 617+ hotels available in Louisville.

















