There are 8 ways to get from Prague to Brussels by plane, train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Brussels Airport
best- Fly from Václav Havel Airport Prague (PRG) to Brussels Airport (BRU)plane PRG - BRU
4h 12m€84–238Bus
cheapest- Take the bus from Praha, ÚAN Florenc to Brussels-North train stationbus N870
13h 29m€55–120Train via Regensburg
- Take the train from Praha Hlavni Nadrazi to Regensburg Hbftrain Ec
- Take the train from Regensburg Hbf to Frankfurt(M) Flughafen Fernbftrain Ice / ...
- Take the train from Frankfurt to Brussels-Nordtrain 79
11h 41m€184–294Drive 865.1 km
- Drive from Prague to Brusselscar 865.1 km
8h 22m€138–199Fly to Amsterdam Airport Schiphol, train
- Fly from Václav Havel Airport Prague (PRG) to Amsterdam Airport Schiphol (AMS)plane PRG - AMS
- Take the train from Schiphol Airport to Brussel-Zuid / Bruxelles-Miditrain
6h 3m€147–364Fly to Brussels South Charleroi Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Brussels South Charleroi Airport (CRL)plane PRG - CRL
- Take the train from Charleroi-Central to Bruxelles-Centraltrain
5h 35m€67–245Train
- Take the train from Praha Hlavní nádraží to Frankfurttrain Drf
- Take the train from Frankfurt to Brussels-Nordtrain 79
12h 59mBus, train
- Take the bus from Praha Hlavní nádraží to Kölnbus Ivano-Frankivsk
- Take the train from Koeln Hbf to Brussel-Zuid / Bruxelles-Miditrain Thalys
21h 55m€222–287
Prague to Brussels by train
Comparing Your Travel Options
The cheapest way to get from Prague to Brussels is to bus which costs €55 - €120 and takes 13h 29m.
The fastest way to get from Prague to Brussels is to fly which takes 4h 12m and costs €80 - €240.
Yes, there is a direct bus departing from Praha, ÚAN Florenc and arriving at Brussels-North train station station. Services depart once daily, and operate every day. The journey takes approximately 13h 29m.
No, there is no direct train from Prague to Brussels. However, there are services departing from Praha Hlavni Nadrazi and arriving at Brussels-Nord via Regensburg Hbf and Frankfurt. The journey, including transfers, takes approximately 11h 41m.
The distance between Prague and Brussels is 723 km. The road distance is 865.1 km.
The best way to get from Prague to Brussels without a car is to train via Regensburg which takes 11h 41m and costs €180 - €300.
It takes approximately 4h 12m to get from Prague to Brussels, including transfers.
Prague to Brussels bus services, operated by FlixBus, depart from Praha, ÚAN Florenc station.
Prague to Brussels train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Brussels is to fly which takes 4h 12m and costs €80 - €240. Alternatively, you can train via Regensburg, which costs €180 - €300 and takes 11h 41m, you could also bus, which costs €55 - €120 and takes 13h 29m.
What companies run services between Prague, Czechia and Brussels, Belgium?
Smartwings, Brussels Airlines, and four other airlines fly from Václav Havel Airport Prague (PRG) to Brussels Airport (BRU) every 3 hours. Alternatively, you can take a train from Praha Hlavni Nadrazi to Brussels-Nord via Regensburg Hbf and Frankfurt in around 11h 41m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Brussels Airport via Munich
- Ave. Duration
- 3h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €65–220
Flights from Václav Havel Airport Prague to Brussels Airport via Frankfurt
- Ave. Duration
- 3h 22m
- When
- Every day
- Estimated price
- €90–550
Flights from Václav Havel Airport Prague to Amsterdam Airport Schiphol via Frankfurt
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €100–600
Flights from Václav Havel Airport Prague to Amsterdam Airport Schiphol via Munich
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- €55–600
- Website
- klm.com
Flights from Václav Havel Airport Prague to Brussels Airport via Amsterdam Airport Schiphol
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- €55–320
Flights from Václav Havel Airport Prague to Amsterdam Airport Schiphol
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €50–300
- Website
- easyjet.com
Flights from Václav Havel Airport Prague to Amsterdam Airport Schiphol
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- €65–210
- Website
- brusselsairlines.com
Flights from Václav Havel Airport Prague to Brussels Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- €65–220
- Website
- ryanair.com
Flights from Václav Havel Airport Prague to Brussels South Charleroi Airport
- Ave. Duration
- 1h 30m
- When
- Monday, Wednesday, and Saturday
- Estimated price
- €50–220
Flights from Václav Havel Airport Prague to Brussels South Charleroi Airport via Venice Treviso
- Ave. Duration
- 3h 55m
- When
- Saturday
- Estimated price
- €50–220
- Website
- smartwings.com
Flights from Václav Havel Airport Prague to Brussels Airport
- Ave. Duration
- 1h 30m
- When
- Monday to Saturday
- Estimated price
- €75–220
- Website
- swiss.com
Flights from Václav Havel Airport Prague to Brussels Airport via Zurich
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- €80–330
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Regensburg Hbf
- Ave. Duration
- 4h 6m
- Frequency
- Hourly
- Estimated price
- €74
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Regensburg Hbf to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 3h 21m
- Frequency
- Hourly
- Estimated price
- €50–100
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Brussels-Nord
- Ave. Duration
- 2h 38m
- Frequency
- Every 4 hours
- Estimated price
- €60–120
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Brussels-Nord
- Ave. Duration
- 2h 38m
- Frequency
- Every 4 hours
- Estimated price
- €60–120
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Frankfurt to Brussels-Nord
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- €75–110
- Website
- Belgian Railways
Train from Charleroi-Central to Bruxelles-Central
- Ave. Duration
- 1h 1m
- Frequency
- Every 20 minutes
- Estimated price
- €11–17
- Website
- Belgian Railways
Train from Frankfurt to Brussels-Nord
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- €75–110
- Website
- Belgian Railways
- Phone
- +44 (0)3432 186 186
- Website
- Eurostar
Train from Schiphol Airport to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- €75–120
- Website
- Eurostar
Train from Koeln Hbf to Brussel-Zuid / Bruxelles-Midi
- Ave. Duration
- 1h 56m
- Frequency
- Every 2 hours
- Estimated price
- €85–140
- Website
- Eurostar
- Website
- LEO Express
Train from Praha Hlavní nádraží to Frankfurt
- Ave. Duration
- 9h 21m
- Frequency
- 3 times a week
- Schedules at
- LEO Express
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Praha, ÚAN Florenc to Brussels-North train station
- Ave. Duration
- 13h 29m
- Frequency
- Once daily
- Estimated price
- €80–120
- Website
- Flixbus
- Phone
- +420 222 222 221
- [email protected]
- Website
- RegioJet
Bus from Praha, ÚAN Florenc to Brussels-North train station
- Ave. Duration
- 12h
- Frequency
- 4 times a week
- Estimated price
- €55–95
- Website
- RegioJet
- Phone
- +38 098-888-11-08
- [email protected]
- Website
- Grand Bus
Bus from Praha Hlavní nádraží to Köln
- Ave. Duration
- 18h 59m
- Frequency
- Once daily
- Estimated price
- €135–150
- Website
- Grand Bus
Want to know more about travelling around Belgium
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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Booking & Getting There
Prague to Brussels bus services, operated by FlixBus, arrive at Brussels-North train station.
Prague to Brussels train services, operated by ÖBB EuroCity, arrive at Regensburg Hbf station.
Yes, the driving distance between Prague to Brussels is 865 km. It takes approximately 8h 22m to drive from Prague to Brussels.
Book your Prague to Brussels train tickets online with Omio.
Book your Prague to Brussels bus tickets online with Omio, FlixBus and two other operators.
There are 1700+ hotels available in Brussels.































