There are 8 ways to get from Prague to Mosbach by bus, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Prague to Neckarsulm station westbus N109
7h 34m€35–60Train via Schwandorf
- Take the train from Praha Hlavni Nadrazi to Schwandorftrain Ec
- Take the train from Schwandorf to Nürnberg Hbftrain
- Take the train from Nuernberg Hbf to Wuerzburg Hbftrain Ice / ...
- Take the train from Wuerzburg Hbf to Osterburkentrain Re
8h 27m€111–139Drive 452.8 km
- Drive from Prague to Mosbachcar 452.8 km
4h 14m€82–118Fly Václav Havel Airport Prague to Frankfurt, train
- Fly from Václav Havel Airport Prague (PRG) to Frankfurt (FRA)plane PRG - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Mosbach, Bahnhoftrain
6h 5m€77–158Bus, train
- Take the bus from Prague - Florenc Main Bus Terminal to Heidelbergbus BlaBlaCar Bus
- Take the train from Heidelberg, Hauptbahnhof to Mosbach, Bahnhoftrain S2 / ...
8h 19m€49–75Train
- Take the train from Praha Hlavni Nadrazi to Heidelberg Hbftrain Ec
- Take the train from Heidelberg, Hauptbahnhof to Mosbach, Bahnhoftrain S2 / ...
12h 19m€206Fly Václav Havel Airport Prague to Stuttgart Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Stuttgart Airport (STR)plane PRG - STR
- Take the train from Stuttgart Hbf to Bad Friedrichshall Hbftrain
7h 27m€114–310Train to Dresden Airport, fly to Frankfurt, train
- Take the train from Praha Hlavni Nadrazi to Dresden Hbftrain
- Fly from Dresden Airport (DRS) to Frankfurt (FRA)plane DRS - FRA
- Take the train from Frankfurt to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Mosbach, Bahnhoftrain
7h 36m€161–375
Prague to Mosbach by bus
Comparing Your Travel Options
The cheapest way to get from Prague to Mosbach is to bus which costs €35 - €60 and takes 7h 34m.
The fastest way to get from Prague to Mosbach is to drive which takes 4h 14m and costs €80 - €120.
No, there is no direct bus from Prague to Mosbach. However, there are services departing from Prague and arriving at Mosbach, Bahnhof via Neckarsulm. The journey, including transfers, takes approximately 7h 34m.
No, there is no direct train from Prague to Mosbach. However, there are services departing from Praha Hlavni Nadrazi and arriving at Mosbach, Bahnhof via Schwandorf, Nuernberg Hbf, Wuerzburg Hbf and Osterburken, Bahnhof. The journey, including transfers, takes approximately 8h 27m.
The distance between Prague and Mosbach is 475 km. The road distance is 452.8 km.
The best way to get from Prague to Mosbach without a car is to bus which takes 7h 34m and costs €35 - €60.
It takes approximately 7h 34m to get from Prague to Mosbach, including transfers.
Prague to Mosbach bus services, operated by FlixBus, depart from Prague station.
Prague to Mosbach train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Mosbach is to bus which takes 7h 34m and costs €35 - €60. Alternatively, you can train via Schwandorf, which costs €110 - €140 and takes 8h 27m.
What companies run services between Prague, Czechia and Mosbach, Baden-Württemberg, Germany?
FlixBus operates a bus from Prague to Neckarsulm station west 6 times a week. Tickets cost €35–60 and the journey takes 5h 55m. Alternatively, you can take a train from Praha Hlavni Nadrazi to Mosbach, Bahnhof via Schwandorf, Nürnberg Hbf, Nuernberg Hbf, Wuerzburg Hbf, and Osterburken, Bahnhof in around 8h 27m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €60–410
Flights from Václav Havel Airport Prague to Frankfurt via Munich
- Ave. Duration
- 2h 50m
- When
- Every day
- Estimated price
- €60–140
Flights from Václav Havel Airport Prague to Stuttgart Airport via Munich
- Ave. Duration
- 2h 55m
- When
- Monday to Saturday
- Estimated price
- €95–350
Flights from Dresden Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €50–350
- Website
- condor.com
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- €55–120
- Website
- austrian.com
Flights from Václav Havel Airport Prague to Stuttgart Airport via Vienna
- Ave. Duration
- 3h 38m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €85–360
- Website
- swiss.com
Flights from Václav Havel Airport Prague to Stuttgart Airport via Zurich
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €90–350
- Website
- airdolomiti.it
Flights from Václav Havel Airport Prague to Frankfurt
- Ave. Duration
- 1h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €130–410
- Website
- lufthansa-city.com
Flights from Dresden Airport to Frankfurt
- Ave. Duration
- 1h 5m
- When
- Monday
- Estimated price
- €50–350
- Phone
- +43 (0) 5 1717
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Schwandorf
- Ave. Duration
- 3h 30m
- Frequency
- Hourly
- Estimated price
- €64
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Heidelberg Hbf
- Ave. Duration
- 11h 1m
- Frequency
- 5 times a day
- Estimated price
- €197
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
Train from Praha Hlavni Nadrazi to Dresden Hbf
- Ave. Duration
- 2h 26m
- Frequency
- 5 times a day
- Estimated price
- €48
- Website
- ÖBB EuroCity
- Website
- ÖBB EuroCity
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Schwandorf to Nürnberg Hbf
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €15
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Nuernberg Hbf to Wuerzburg Hbf
- Ave. Duration
- 1h 12m
- Frequency
- Hourly
- Estimated price
- €16
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Wuerzburg Hbf to Osterburken
- Ave. Duration
- 1h 12m
- Frequency
- Every 2 hours
- Estimated price
- €13
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mannheim, Hauptbahnhof to Mosbach, Bahnhof
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €12
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Heidelberg, Hauptbahnhof to Mosbach, Bahnhof
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- €9
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Heidelberg, Hauptbahnhof to Mosbach, Bahnhof
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- €9
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Stuttgart Hbf to Bad Friedrichshall Hbf
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- €10
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Mannheim, Hauptbahnhof to Mosbach, Bahnhof
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €12
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Nuernberg Hbf to Wuerzburg Hbf
- Ave. Duration
- 52 min
- Frequency
- Hourly
- Estimated price
- €16–30
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €11–22
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- €11–22
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg
Train from Wuerzburg Hbf to Osterburken
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €14–26
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €14–17
- 1st Class Ticket
- €18–26
Train from Stuttgart Hbf to Bad Friedrichshall Hbf
- Ave. Duration
- 49 min
- Frequency
- Hourly
- Estimated price
- €12–23
- Schedules at
- Arverio Baden-Württemberg
- 2nd Class Ticket
- €12–15
- 1st Class Ticket
- €16–23
- Phone
- +49 711 400 534 44
- [email protected]
- Website
- Arverio Baden-Württemberg GmbH
Train from Wuerzburg Hbf to Osterburken
- Ave. Duration
- 53 min
- Frequency
- Hourly
- Estimated price
- €13–19
- Schedules at
- Arverio Baden-Württemberg GmbH
Train from Stuttgart Hbf to Bad Friedrichshall Hbf
- Ave. Duration
- 49 min
- Frequency
- Hourly
- Estimated price
- €12–17
- Schedules at
- Arverio Baden-Württemberg GmbH
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 32 min
- Frequency
- Every 4 hours
- Estimated price
- €8–15
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Mannheim, Hauptbahnhof
- Ave. Duration
- 32 min
- Frequency
- Every 4 hours
- Estimated price
- €8–15
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +420 221 111 122
- [email protected]
- Website
- Czech Railways (ČD)
Train from Praha Hlavni Nadrazi to Dresden Hbf
- Ave. Duration
- 2h 18m
- Frequency
- Hourly
- Estimated price
- €17–25
- Website
- Czech Railways (ČD)
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Prague to Neckarsulm station west
- Ave. Duration
- 5h 55m
- Frequency
- 6 times a week
- Estimated price
- €35–60
- Website
- Flixbus
- Phone
- +3 318 576 2228
- Website
- BlaBlaCar Bus
Bus from Prague - Florenc Main Bus Terminal to Heidelberg
- Ave. Duration
- 6h 55m
- Frequency
- Twice daily
- Estimated price
- €40–70
- Website
- BlaBlaCar Bus
Want to know more about travelling around Germany
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Booking & Getting There
Prague to Mosbach bus services, operated by FlixBus, arrive at Neckarsulm station west.
Prague to Mosbach train services, operated by ÖBB EuroCity, arrive at Schwandorf station.
Yes, the driving distance between Prague to Mosbach is 453 km. It takes approximately 4h 14m to drive from Prague to Mosbach.
Book your Prague to Mosbach train tickets online with Omio.
There are 571+ hotels available in Mosbach.












































