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How to get fromPurdue University to St. Louisby bus (Amtrak, Greyhound), bus, train, car, plane, bus (Greyhound), train (Amtrak), or shuttle

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There are 9 ways to get from Purdue University to St. Louis by bus (Amtrak, Greyhound), bus, train, car, plane, bus (Greyhound), train (Amtrak), or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Lafayette Amtrak Station to Indianapolis Union Stationbus bus Chicago
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    7h 32m
    $55–111

  2. Drive  253 mi

    cheapest
    1. Drive from Purdue University to St. Louiscar car 253 mi
    4h 56m
    $42–61

  3. Bus, train

    1. Take the bus from Lafayette Bus Stop to Chicago Bus Stationbus bus FlixBus 2515 / ...
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    9h 29m
    $170–276

  4. Fly from Purdue University Airport

    1. Fly from Purdue University Airport (LAF) to Lambert–St. Louis International Airport (STL)plane plane LAF - STL
    6h 26m
    $74–464

  5. Bus via Indianapolis Airport (IND)

    1. Take the bus from Co-Rec Circle Drive to Indianapolis Airportbus bus Purdue
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    8h 4m
    $71–104

  6. Train (Amtrak)

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    10h 27m
    $216–351

  7. Shuttle to Indianapolis, fly

    1. Take a shuttle bus from Ford Hall - Stadium Ave to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Lambert–St. Louis International Airport (STL)plane plane IND - STL
    7h 21m
    $126–636

  8. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    5h 48m
    $379–774

  9. Bus to Chicago Midway International Airport, fly

    1. Take the bus from Lafayette Bus Stop to Chicago Bus Stationbus bus
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    7h 31m
    $110–644

Purdue University to St. Louis by foot and bus

Calendar7Weekly Services
Duration7h 32mAverage Duration
Ticket$55Cheapest Price
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Comparing Your Travel Options

Map of how to get from Purdue University to St. Louis.ExpandLaunch map view
  • Distance: 308.1 mi
  • Duration: 7h 32m

What companies run services between Purdue University, IN, USA and St. Louis, MO, USA?

You can take a vehicle from Purdue University to St Louis Bus Station via Aspire Apts at Discovery Park: BUS011, 2nd St & Columbia St, Lafayette Amtrak Station, and Indianapolis Union Station in around 7h 32m. Alternatively, United Airlines flies from Purdue University Airport (LAF) to Lambert–St. Louis International Airport (STL) twice daily.

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Need to know: Greyhound

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