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How to get fromSiena to Agrigentoby train, plane, train (Trenitalia), car, car ferry, or bus

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There are 10 ways to get from Siena to Agrigento by train, plane, train (Trenitalia), car, car ferry, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Florence Peretola Airport, fly to Palermo Airport, train

    best
    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Palermo Airport (PMO)plane plane FLR - PMO
    3. Take the train from Palermo Aeroporto to Agrigento Centraletrain train
    7h 59m
    €63–245

  2. Train to Florence Peretola Airport, fly to Catania–Fontanarossa Airport, bus

    cheapest
    1. Take the train from Siena to Firenze S.M.N.train train
    2. Fly from Florence Peretola Airport (FLR) to Catania–Fontanarossa Airport (CTA)plane plane FLR - CTA
    3. Take the bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rossellibus bus
    8h 12m
    €45–200

  3. Train

    1. Take the train from Siena to Firenze S.M.N.train train Re
    2. Take the train from Firenze S.M.N. to Roma Terminitrain train Fr
    3. Take the train from Roma Termini to Termini Imeresetrain train Ic
    4. Take the train from Termini Imerese to Agrigento Centraletrain train Re
    17h 29m
    €142–262

  4. Drive, car ferry

    1. Drive from Siena to Civitavecchia Portcar car
    2. Take the carferry from Civitavecchia Port to Palermo Portocarferry car ferry
    3. Drive from Palermo Porto to Agrigentocar car
    17h 53m
    €115–168

  5. Bus

    1. Take the bus from Siena to Agrigentobus bus N528
    18h 45m
    €110–170

  6. Train, train to Pisa International Airport, fly to Palermo Airport

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Palermo Airport (PMO)plane plane PSA - PMO
    4. Take the train from Palermo Aeroporto to Agrigento Centraletrain train
    8h 2m
    €73–273

  7. Train, train to Bologna Guglielmo Marconi Airport, fly to Palermo Airport

    1. Take the train from Siena to Firenze S.M.N.train train
    2. Take the train from Firenze S.M.N. to Bologna Centraletrain train
    3. Fly from Bologna Guglielmo Marconi Airport (BLQ) to Palermo Airport (PMO)plane plane BLQ - PMO
    4. Take the train from Palermo Aeroporto to Agrigento Centraletrain train
    8h 41m
    €54–243

  8. Train, train to Pisa International Airport, fly to Catania–Fontanarossa Airport, bus

    1. Take the train from Siena to Empolitrain train
    2. Take the train from Empoli to Pisa Centraletrain train
    3. Fly from Pisa International Airport (PSA) to Catania–Fontanarossa Airport (CTA)plane plane PSA - CTA
    4. Take the bus from Catania Aeroporto Fontanarossa to Agrigento Piazzale Rossellibus bus
    8h 20m
    €64–238

  9. Bus to Perugia Sant'Egidio Airport, fly to Palermo Airport, train

    1. Take the bus from Siena to Perugiabus bus
    2. Fly from Perugia Sant'Egidio Airport (PEG) to Palermo Airport (PMO)plane plane PEG - PMO
    3. Take the train from Palermo Aeroporto to Agrigento Centraletrain train
    9h 4m
    €72–296

  10. Bus via Florence

    1. Take the bus from Siena-Via Tozzi to Firenze Autostazionebus bus 131R / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Agrigento Piazzale Rossellibus bus
    23h 11m
    €207–288

Siena to Agrigento by train

Calendar28Weekly Trains
Duration17h 29mAverage Duration
Ticket€142Cheapest Price
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Comparing Your Travel Options

Map of how to get from Siena to Agrigento.ExpandLaunch map view
  • Distance: 911.7 km
  • Duration: 7h 59m

What companies run services between Siena, Italy and Agrigento, Italy?

You can take a train from Siena to Agrigento Centrale via Firenze S.M.N., Roma Termini, and Termini Imerese in around 17h 29m. Alternatively, FlixBus operates a bus from Siena to Agrigento once daily. Tickets cost €110–170 and the journey takes 18h 45m.

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