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How to get fromWisconsin to Louisvilleby bus (Greyhound, Flixbus, Amtrak), train, bus, car, plane, or bus (Flixbus, Amtrak)

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There are 9 ways to get from Wisconsin to Louisville by bus (Greyhound, Flixbus, Amtrak), train, bus, car, plane, or bus (Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus Greyhound US0150
    2. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    9h 29m
    $64–83

  2. Train, bus (Amtrak)

    1. Take the train from Milwaukee to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    10h 18m
    $169–287

  3. Drive  382.5 mi

    1. Drive from Milwaukee to Louisvillecar car 382.5 mi
    6h 44m
    $64–92

  4. Fly General Mitchell International Airport to Louisville International Airport

    1. Fly from General Mitchell International Airport (MKE) to Louisville International Airport (SDF)plane plane MKE - SDF
    5h 46m
    $123–805

  5. Bus via Lafayette

    1. Take the bus from Milwaukee Intermodal Station to Lafayette Bus Stopbus bus FlixBus 2511
    2. Take the bus from Lafayette Amtrak Station to Louisville, KYbus bus Chicago
    10h 5m
    $64–100

  6. Bus to Chicago O'Hare International Airport, fly to Louisville International Airport

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    5h 36m
    $104–484

  7. Train to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the train from Kenosha to Chicago OTCtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    6h 7m
    $120–766

  8. Bus to Chicago O'Hare International Airport, fly to Blue Grass Airport, drive

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 1 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 38m
    $89–329

  9. Bus to Minneapolis–Saint Paul International Airport, fly to Louisville International Airport

    1. Take the bus from Eau Claire Amtrak Bus Stop to Mall of America - IKEA - Bloomingtonbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Louisville International Airport (SDF)plane plane MSP - SDF
    6h 23m
    $170–843

Wisconsin to Louisville by bus and foot

Calendar14Weekly Services
Duration9h 29mAverage Duration
Ticket$64Cheapest Price
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Comparing Your Travel Options

Map of how to get from Wisconsin to Louisville.ExpandLaunch map view
  • Distance: 387.9 mi
  • Duration: 9h 29m

What companies run services between Wisconsin, USA and Louisville, KY, USA?

You can take a bus from Milwaukee Intermodal Station to Louisville, KY via Chicago Bus Station and Chicago Union Station in around 9h 29m. Alternatively, Southwest Airlines, United Airlines, and two other airlines fly from General Mitchell International Airport (MKE) to Louisville International Airport (SDF) hourly.

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Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

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Need to know: Greyhound

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